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Role of hepatic PKCβ in nutritional regulation of hepatic glycogen synthesis

The signaling mechanisms by which dietary fat and cholesterol signals regulate central pathways of glucose homeostasis are not completely understood. By using a hepatocyte-specific PKCβ-deficient (PKCβ(Hep–/–)) mouse model, we demonstrated the role of hepatic PKCβ in slowing disposal of glucose over...

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Detalles Bibliográficos
Autores principales: Shu, Yaoling, Hassan, Faizule, Ostrowski, Michael C., Mehta, Kamal D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525638/
https://www.ncbi.nlm.nih.gov/pubmed/34622807
http://dx.doi.org/10.1172/jci.insight.149023