p300 suppresses the transition of myelodysplastic syndromes to acute myeloid leukemia

Myelodysplastic syndromes (MDS) are hematopoietic stem and progenitor cell (HSPC) malignancies characterized by ineffective hematopoiesis and an increased risk of leukemia transformation. Epigenetic regulators are recurrently mutated in MDS, directly implicating epigenetic dysregulation in MDS patho...

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Detalles Bibliográficos
Autores principales: Man, Na, Mas, Gloria, Karl, Daniel L., Sun, Jun, Liu, Fan, Yang, Qin, Torres-Martin, Miguel, Itonaga, Hidehiro, Martinez, Concepcion, Chen, Shi, Xu, Ye, Duffort, Stephanie, Hamard, Pierre-Jacques, Chen, Chuan, Zucconi, Beth E., Cimmino, Luisa, Yang, Feng-Chun, Xu, Mingjiang, Cole, Philip A., Figueroa, Maria E., Nimer, Stephen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525640/
https://www.ncbi.nlm.nih.gov/pubmed/34622806
http://dx.doi.org/10.1172/jci.insight.138478

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