A dynamic mucin mRNA signature associates with COVID-19 disease presentation and severity

BACKGROUND: SARS-CoV-2 infection induces mucin overexpression, further promoting disease. Given that mucins are critical components of innate immunity, unraveling their expression profiles that dictate the course of disease could greatly enhance our understanding and management of COVID-19. METHODS:...

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Detalles Bibliográficos
Autores principales: Smet, Annemieke, Breugelmans, Tom, Michiels, Johan, Lamote, Kevin, Arras, Wout, De Man, Joris G., Heyndrickx, Leo, Hauner, Anne, Huizing, Manon, Malhotra-Kumar, Surbhi, Lammens, Martin, Hotterbeekx, An, Kumar-Singh, Samir, Verstraeten, Aline, Loeys, Bart, Verhoeven, Veronique, Jacobs, Rita, Dams, Karolien, Coenen, Samuel, Ariën, Kevin K., Jorens, Philippe G., De Winter, Benedicte Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525642/
https://www.ncbi.nlm.nih.gov/pubmed/34448730
http://dx.doi.org/10.1172/jci.insight.151777

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