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New targets of morphine postconditioning protection of the myocardium in ischemia/reperfusion injury: Involvement of HSP90/Akt and C5a/NF-κB

BACKGROUND: Activation of the complement component 5a (C5a) and nuclear factor κB (NF-κB) signaling is an important feature of myocardial ischemia/reperfusion (I/R) injury and recent studies show that morphine postconditioning (MP) attenuates the myocardial injury. However, the mediating cardioprote...

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Detalles Bibliográficos
Autores principales: Tu, Rong-Hui, Wang, Dong-Xiao, Zhong, Guo-Qiang, Meng, Jian-Jun, Wen, Hong, Jie-Feng, Bi, Qi, He, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525660/
https://www.ncbi.nlm.nih.gov/pubmed/34722891
http://dx.doi.org/10.1515/med-2021-0340

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