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New targets of morphine postconditioning protection of the myocardium in ischemia/reperfusion injury: Involvement of HSP90/Akt and C5a/NF-κB
BACKGROUND: Activation of the complement component 5a (C5a) and nuclear factor κB (NF-κB) signaling is an important feature of myocardial ischemia/reperfusion (I/R) injury and recent studies show that morphine postconditioning (MP) attenuates the myocardial injury. However, the mediating cardioprote...
Autores principales: | Tu, Rong-Hui, Wang, Dong-Xiao, Zhong, Guo-Qiang, Meng, Jian-Jun, Wen, Hong, Jie-Feng, Bi, Qi, He, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525660/ https://www.ncbi.nlm.nih.gov/pubmed/34722891 http://dx.doi.org/10.1515/med-2021-0340 |
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