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Polycythemia in a Patient With Atonic Bladder and Hydronephrosis

Kidneys influence the production of red blood cells by secreting most of the erythropoietin (EPO) in adults. Consequently, renal diseases often impact erythropoiesis and hemoglobin levels. Chronic kidney diseases lead to anemia due to EPO deficiency. However, erythrocytosis can occur in patients wit...

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Autores principales: Katiyar, Vatsala, Aijaz, Talha, Lingamaneni, Prasanth, Vohra, Ishaan, Cisak, Kamila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525674/
https://www.ncbi.nlm.nih.gov/pubmed/34692308
http://dx.doi.org/10.7759/cureus.18094
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author Katiyar, Vatsala
Aijaz, Talha
Lingamaneni, Prasanth
Vohra, Ishaan
Cisak, Kamila
author_facet Katiyar, Vatsala
Aijaz, Talha
Lingamaneni, Prasanth
Vohra, Ishaan
Cisak, Kamila
author_sort Katiyar, Vatsala
collection PubMed
description Kidneys influence the production of red blood cells by secreting most of the erythropoietin (EPO) in adults. Consequently, renal diseases often impact erythropoiesis and hemoglobin levels. Chronic kidney diseases lead to anemia due to EPO deficiency. However, erythrocytosis can occur in patients with cystic diseases of the kidney and renal artery stenosis due to upregulation of hypoxia-inducible factors (HIFs) and increased EPO production. Here, we present a patient with secondary polycythemia who was found to have atonic bladder and hydronephrosis. Resolution of hydronephrosis led to the reversal of erythrocytosis, highlighting the intricate regulation of red cell production.
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spelling pubmed-85256742021-10-22 Polycythemia in a Patient With Atonic Bladder and Hydronephrosis Katiyar, Vatsala Aijaz, Talha Lingamaneni, Prasanth Vohra, Ishaan Cisak, Kamila Cureus Internal Medicine Kidneys influence the production of red blood cells by secreting most of the erythropoietin (EPO) in adults. Consequently, renal diseases often impact erythropoiesis and hemoglobin levels. Chronic kidney diseases lead to anemia due to EPO deficiency. However, erythrocytosis can occur in patients with cystic diseases of the kidney and renal artery stenosis due to upregulation of hypoxia-inducible factors (HIFs) and increased EPO production. Here, we present a patient with secondary polycythemia who was found to have atonic bladder and hydronephrosis. Resolution of hydronephrosis led to the reversal of erythrocytosis, highlighting the intricate regulation of red cell production. Cureus 2021-09-19 /pmc/articles/PMC8525674/ /pubmed/34692308 http://dx.doi.org/10.7759/cureus.18094 Text en Copyright © 2021, Katiyar et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Katiyar, Vatsala
Aijaz, Talha
Lingamaneni, Prasanth
Vohra, Ishaan
Cisak, Kamila
Polycythemia in a Patient With Atonic Bladder and Hydronephrosis
title Polycythemia in a Patient With Atonic Bladder and Hydronephrosis
title_full Polycythemia in a Patient With Atonic Bladder and Hydronephrosis
title_fullStr Polycythemia in a Patient With Atonic Bladder and Hydronephrosis
title_full_unstemmed Polycythemia in a Patient With Atonic Bladder and Hydronephrosis
title_short Polycythemia in a Patient With Atonic Bladder and Hydronephrosis
title_sort polycythemia in a patient with atonic bladder and hydronephrosis
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525674/
https://www.ncbi.nlm.nih.gov/pubmed/34692308
http://dx.doi.org/10.7759/cureus.18094
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