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Polycythemia in a Patient With Atonic Bladder and Hydronephrosis
Kidneys influence the production of red blood cells by secreting most of the erythropoietin (EPO) in adults. Consequently, renal diseases often impact erythropoiesis and hemoglobin levels. Chronic kidney diseases lead to anemia due to EPO deficiency. However, erythrocytosis can occur in patients wit...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525674/ https://www.ncbi.nlm.nih.gov/pubmed/34692308 http://dx.doi.org/10.7759/cureus.18094 |
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author | Katiyar, Vatsala Aijaz, Talha Lingamaneni, Prasanth Vohra, Ishaan Cisak, Kamila |
author_facet | Katiyar, Vatsala Aijaz, Talha Lingamaneni, Prasanth Vohra, Ishaan Cisak, Kamila |
author_sort | Katiyar, Vatsala |
collection | PubMed |
description | Kidneys influence the production of red blood cells by secreting most of the erythropoietin (EPO) in adults. Consequently, renal diseases often impact erythropoiesis and hemoglobin levels. Chronic kidney diseases lead to anemia due to EPO deficiency. However, erythrocytosis can occur in patients with cystic diseases of the kidney and renal artery stenosis due to upregulation of hypoxia-inducible factors (HIFs) and increased EPO production. Here, we present a patient with secondary polycythemia who was found to have atonic bladder and hydronephrosis. Resolution of hydronephrosis led to the reversal of erythrocytosis, highlighting the intricate regulation of red cell production. |
format | Online Article Text |
id | pubmed-8525674 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-85256742021-10-22 Polycythemia in a Patient With Atonic Bladder and Hydronephrosis Katiyar, Vatsala Aijaz, Talha Lingamaneni, Prasanth Vohra, Ishaan Cisak, Kamila Cureus Internal Medicine Kidneys influence the production of red blood cells by secreting most of the erythropoietin (EPO) in adults. Consequently, renal diseases often impact erythropoiesis and hemoglobin levels. Chronic kidney diseases lead to anemia due to EPO deficiency. However, erythrocytosis can occur in patients with cystic diseases of the kidney and renal artery stenosis due to upregulation of hypoxia-inducible factors (HIFs) and increased EPO production. Here, we present a patient with secondary polycythemia who was found to have atonic bladder and hydronephrosis. Resolution of hydronephrosis led to the reversal of erythrocytosis, highlighting the intricate regulation of red cell production. Cureus 2021-09-19 /pmc/articles/PMC8525674/ /pubmed/34692308 http://dx.doi.org/10.7759/cureus.18094 Text en Copyright © 2021, Katiyar et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Katiyar, Vatsala Aijaz, Talha Lingamaneni, Prasanth Vohra, Ishaan Cisak, Kamila Polycythemia in a Patient With Atonic Bladder and Hydronephrosis |
title | Polycythemia in a Patient With Atonic Bladder and Hydronephrosis |
title_full | Polycythemia in a Patient With Atonic Bladder and Hydronephrosis |
title_fullStr | Polycythemia in a Patient With Atonic Bladder and Hydronephrosis |
title_full_unstemmed | Polycythemia in a Patient With Atonic Bladder and Hydronephrosis |
title_short | Polycythemia in a Patient With Atonic Bladder and Hydronephrosis |
title_sort | polycythemia in a patient with atonic bladder and hydronephrosis |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525674/ https://www.ncbi.nlm.nih.gov/pubmed/34692308 http://dx.doi.org/10.7759/cureus.18094 |
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