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Neutrophil-Derived Proteases Contribute to the Pathogenesis of Early Diabetic Retinopathy

PURPOSE: Previous studies indicate that leukocytes, notably neutrophils, play a causal role in the capillary degeneration observed in diabetic retinopathy (DR), however, the mechanism by which they cause such degeneration is unknown. Neutrophil elastase (NE) is a protease released by neutrophils whi...

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Detalles Bibliográficos
Autores principales: Lessieur, Emma M., Liu, Haitao, Saadane, Aicha, Du, Yunpeng, Tang, Jie, Kiser, Jianying, Kern, Timothy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525836/
https://www.ncbi.nlm.nih.gov/pubmed/34643662
http://dx.doi.org/10.1167/iovs.62.13.7