Cargando…
Health Outcomes among Adults Initiating Medical Cannabis for Chronic Pain: A 3-month Prospective Study Incorporating Ecological Momentary Assessment (EMA)
In response to the need of more rigorous data on medical cannabis and chronic pain, we conducted a 3-month prospective study incorporating ecological momentary assessment (EMA) to examine the effects of medical cannabis on pain, anxiety/depression, sleep, and quality of life. Data were collected fro...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Society on Marijuana
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525881/ https://www.ncbi.nlm.nih.gov/pubmed/34671723 http://dx.doi.org/10.26828/cannabis/2021.02.006 |
_version_ | 1784585772892946432 |
---|---|
author | Wang, Yan Jacques, Jennifer Jean Li, Zhigang Sibille, Kimberly T. Cook, Robert L. |
author_facet | Wang, Yan Jacques, Jennifer Jean Li, Zhigang Sibille, Kimberly T. Cook, Robert L. |
author_sort | Wang, Yan |
collection | PubMed |
description | In response to the need of more rigorous data on medical cannabis and chronic pain, we conducted a 3-month prospective study incorporating ecological momentary assessment (EMA) to examine the effects of medical cannabis on pain, anxiety/depression, sleep, and quality of life. Data were collected from 46 adults (Mean age=55.7±11.9, 52.2% male) newly initiating medical cannabis treatment for chronic pain. Participants completed a baseline survey, EMA for approximately 1 week pre- and up to 3 weeks post-medical cannabis treatment, and a 3-month follow-up survey. The self-reported EMA data (2535 random and 705 daily assessments) indicated significant reductions in momentary pain intensity (b = -16.5, p < .001, 16.5 points reduction on 0-100 visual analog) and anxiety (b = -0.89, p < .05), and significant increase in daily sleep duration (b = 0.34, p < .01) and sleep quality (b = 0.32, p <.001) after participants initiated medical cannabis for a few weeks. At 3 months, self-reported survey data showed significantly lower levels of worst pain (t = -2.38, p < .05), pain interference (t = -3.82, p < .05), and depression (t = -3.43, p < .01), as well as increased sleep duration (t = 3.95, p < .001), sleep quality (t = -3.04, p < .01), and quality of life (t = 4.48, p < .001) compared to baseline. In our sample of primarily middle-aged and older adults with chronic pain, medical cannabis was associated with reduced pain intensity/inference, lower anxiety/depression, and improved sleep and quality of life. |
format | Online Article Text |
id | pubmed-8525881 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Research Society on Marijuana |
record_format | MEDLINE/PubMed |
spelling | pubmed-85258812021-10-19 Health Outcomes among Adults Initiating Medical Cannabis for Chronic Pain: A 3-month Prospective Study Incorporating Ecological Momentary Assessment (EMA) Wang, Yan Jacques, Jennifer Jean Li, Zhigang Sibille, Kimberly T. Cook, Robert L. Cannabis Research Article In response to the need of more rigorous data on medical cannabis and chronic pain, we conducted a 3-month prospective study incorporating ecological momentary assessment (EMA) to examine the effects of medical cannabis on pain, anxiety/depression, sleep, and quality of life. Data were collected from 46 adults (Mean age=55.7±11.9, 52.2% male) newly initiating medical cannabis treatment for chronic pain. Participants completed a baseline survey, EMA for approximately 1 week pre- and up to 3 weeks post-medical cannabis treatment, and a 3-month follow-up survey. The self-reported EMA data (2535 random and 705 daily assessments) indicated significant reductions in momentary pain intensity (b = -16.5, p < .001, 16.5 points reduction on 0-100 visual analog) and anxiety (b = -0.89, p < .05), and significant increase in daily sleep duration (b = 0.34, p < .01) and sleep quality (b = 0.32, p <.001) after participants initiated medical cannabis for a few weeks. At 3 months, self-reported survey data showed significantly lower levels of worst pain (t = -2.38, p < .05), pain interference (t = -3.82, p < .05), and depression (t = -3.43, p < .01), as well as increased sleep duration (t = 3.95, p < .001), sleep quality (t = -3.04, p < .01), and quality of life (t = 4.48, p < .001) compared to baseline. In our sample of primarily middle-aged and older adults with chronic pain, medical cannabis was associated with reduced pain intensity/inference, lower anxiety/depression, and improved sleep and quality of life. Research Society on Marijuana 2021-10-01 /pmc/articles/PMC8525881/ /pubmed/34671723 http://dx.doi.org/10.26828/cannabis/2021.02.006 Text en © 2021 Authors et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits unrestricted use, distribution, and reproduction, provided the original author and source are credited, the original sources is not modified, and the source is not used for commercial purposes. |
spellingShingle | Research Article Wang, Yan Jacques, Jennifer Jean Li, Zhigang Sibille, Kimberly T. Cook, Robert L. Health Outcomes among Adults Initiating Medical Cannabis for Chronic Pain: A 3-month Prospective Study Incorporating Ecological Momentary Assessment (EMA) |
title | Health Outcomes among Adults Initiating Medical Cannabis for Chronic Pain: A 3-month Prospective Study Incorporating Ecological Momentary Assessment (EMA) |
title_full | Health Outcomes among Adults Initiating Medical Cannabis for Chronic Pain: A 3-month Prospective Study Incorporating Ecological Momentary Assessment (EMA) |
title_fullStr | Health Outcomes among Adults Initiating Medical Cannabis for Chronic Pain: A 3-month Prospective Study Incorporating Ecological Momentary Assessment (EMA) |
title_full_unstemmed | Health Outcomes among Adults Initiating Medical Cannabis for Chronic Pain: A 3-month Prospective Study Incorporating Ecological Momentary Assessment (EMA) |
title_short | Health Outcomes among Adults Initiating Medical Cannabis for Chronic Pain: A 3-month Prospective Study Incorporating Ecological Momentary Assessment (EMA) |
title_sort | health outcomes among adults initiating medical cannabis for chronic pain: a 3-month prospective study incorporating ecological momentary assessment (ema) |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525881/ https://www.ncbi.nlm.nih.gov/pubmed/34671723 http://dx.doi.org/10.26828/cannabis/2021.02.006 |
work_keys_str_mv | AT wangyan healthoutcomesamongadultsinitiatingmedicalcannabisforchronicpaina3monthprospectivestudyincorporatingecologicalmomentaryassessmentema AT jacquesjenniferjean healthoutcomesamongadultsinitiatingmedicalcannabisforchronicpaina3monthprospectivestudyincorporatingecologicalmomentaryassessmentema AT lizhigang healthoutcomesamongadultsinitiatingmedicalcannabisforchronicpaina3monthprospectivestudyincorporatingecologicalmomentaryassessmentema AT sibillekimberlyt healthoutcomesamongadultsinitiatingmedicalcannabisforchronicpaina3monthprospectivestudyincorporatingecologicalmomentaryassessmentema AT cookrobertl healthoutcomesamongadultsinitiatingmedicalcannabisforchronicpaina3monthprospectivestudyincorporatingecologicalmomentaryassessmentema |