Inhibiting NLRP3 inflammasome attenuates apoptosis in contrast-induced acute kidney injury through the upregulation of HIF1A and BNIP3-mediated mitophagy

The pathogenetic mechanism of contrast-induced acute kidney injury (CI-AKI), which is the third most common cause of hospital-acquired AKI, has not been elucidated. Previously, we demonstrated that renal injury and cell apoptosis were attenuated in nlrp3 knockout CI-AKI mice. Here, we investigated t...

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Detalles Bibliográficos
Autores principales: Lin, Qisheng, Li, Shu, Jiang, Na, Jin, Haijiao, Shao, Xinghua, Zhu, Xuying, Wu, Jingkui, Zhang, Minfang, Zhang, Zhen, Shen, Jianxiao, Zhou, Wenyan, Gu, Leyi, Lu, Renhua, Ni, Zhaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525960/
https://www.ncbi.nlm.nih.gov/pubmed/33345685
http://dx.doi.org/10.1080/15548627.2020.1848971

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