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Oral microbial diversity analysis among atrophic glossitis patients and healthy individuals
Atrophic glossitis is a common disease in oral mucosal diseases. The Current studies have found the human oral cavity contains numerous and diverse microorganisms, their composition and diversity can be changed by various oral diseases. To understand the composition and diversity of oral microbiome...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526005/ https://www.ncbi.nlm.nih.gov/pubmed/34676060 http://dx.doi.org/10.1080/20002297.2021.1984063 |
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author | Li, Hong Sun, Jing Wang, Xiaoyan Shi, Jing |
author_facet | Li, Hong Sun, Jing Wang, Xiaoyan Shi, Jing |
author_sort | Li, Hong |
collection | PubMed |
description | Atrophic glossitis is a common disease in oral mucosal diseases. The Current studies have found the human oral cavity contains numerous and diverse microorganisms, their composition and diversity can be changed by various oral diseases. To understand the composition and diversity of oral microbiome in atrophic glossitis is better to explore the cause and mechanism of atrophic glossitis. The salivary microbiome is comprised of indigenous oral microorganisms that are specific to each person, exhibits long-term stability. We used llumina MiSeq high-throughput sequencing based on the V3-V4 region of the bacterial 16S rRNA gene and the internal transcribed spacer (ITS) region of fungal rRNA genes from saliva in atrophic glossitis patients and healthy individuals to explore the composition and diversity of oral microbiome. In our reports, it showed a lower diversity of bacteria and fungi in atrophic glossitis patients than in healthy individuals. The data further suggests that Lactobacillus and Saccharomycetales were potential indicators for the initiation and development of atrophic glossitis. Moreover, we also discuss the relationship between the oral microbial ecology and atrophic glossitis. |
format | Online Article Text |
id | pubmed-8526005 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-85260052021-10-20 Oral microbial diversity analysis among atrophic glossitis patients and healthy individuals Li, Hong Sun, Jing Wang, Xiaoyan Shi, Jing J Oral Microbiol Original Article Atrophic glossitis is a common disease in oral mucosal diseases. The Current studies have found the human oral cavity contains numerous and diverse microorganisms, their composition and diversity can be changed by various oral diseases. To understand the composition and diversity of oral microbiome in atrophic glossitis is better to explore the cause and mechanism of atrophic glossitis. The salivary microbiome is comprised of indigenous oral microorganisms that are specific to each person, exhibits long-term stability. We used llumina MiSeq high-throughput sequencing based on the V3-V4 region of the bacterial 16S rRNA gene and the internal transcribed spacer (ITS) region of fungal rRNA genes from saliva in atrophic glossitis patients and healthy individuals to explore the composition and diversity of oral microbiome. In our reports, it showed a lower diversity of bacteria and fungi in atrophic glossitis patients than in healthy individuals. The data further suggests that Lactobacillus and Saccharomycetales were potential indicators for the initiation and development of atrophic glossitis. Moreover, we also discuss the relationship between the oral microbial ecology and atrophic glossitis. Taylor & Francis 2021-10-07 /pmc/articles/PMC8526005/ /pubmed/34676060 http://dx.doi.org/10.1080/20002297.2021.1984063 Text en © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Li, Hong Sun, Jing Wang, Xiaoyan Shi, Jing Oral microbial diversity analysis among atrophic glossitis patients and healthy individuals |
title | Oral microbial diversity analysis among atrophic glossitis patients and healthy individuals |
title_full | Oral microbial diversity analysis among atrophic glossitis patients and healthy individuals |
title_fullStr | Oral microbial diversity analysis among atrophic glossitis patients and healthy individuals |
title_full_unstemmed | Oral microbial diversity analysis among atrophic glossitis patients and healthy individuals |
title_short | Oral microbial diversity analysis among atrophic glossitis patients and healthy individuals |
title_sort | oral microbial diversity analysis among atrophic glossitis patients and healthy individuals |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526005/ https://www.ncbi.nlm.nih.gov/pubmed/34676060 http://dx.doi.org/10.1080/20002297.2021.1984063 |
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