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Genistein alleviates H(2)O(2)-induced senescence of human umbilical vein endothelial cells via regulating the TXNIP/NLRP3 axis

CONTEXT: Genistein (Gen) has shown protective effects against ageing process. OBJECTIVE: To explore the role of Gen on the senescence of H(2)O(2)-induced human umbilical vein endothelial cells (HUVECs) and investigate the possible mechanism. MATERIALS AND METHODS: HUVECs were treated with different...

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Detalles Bibliográficos
Autores principales: Wu, Guihua, Li, Siming, Qu, Guangjin, Hua, Jiajia, Zong, Jing, Li, Xiaofeng, Xu, Fanghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526007/
https://www.ncbi.nlm.nih.gov/pubmed/34663173
http://dx.doi.org/10.1080/13880209.2021.1979052