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GLIPR2 is a negative regulator of autophagy and the BECN1-ATG14-containing phosphatidylinositol 3-kinase complex

A key mediator of macroautophagy/autophagy induction is the class III phosphatidylinositol 3-kinase complex I (PtdIns3K-C1) consisting of PIK3C3/VPS34, PIK3R4/VPS15, BECN1, and ATG14. Although several proteins are known to enhance or decrease PtdIns3K-C1 activity, our understanding of the molecular...

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Detalles Bibliográficos
Autores principales: Zhao, Yuting, Zou, Zhongju, Sun, Daxiao, Li, Yue, Sinha, Sangita C., Yu, Li, Bennett, Lynda, Levine, Beth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526008/
https://www.ncbi.nlm.nih.gov/pubmed/33222586
http://dx.doi.org/10.1080/15548627.2020.1847798