HPV sensitizes OPSCC cells to cisplatin-induced apoptosis by inhibiting autophagy through E7-mediated degradation of AMBRA1

Oropharyngeal squamous cell carcinoma (OPSCC) is an increasing world health problem with a more favorable prognosis for patients with human papillomavirus (HPV)-positive tumors compared to those with HPV-negative OPSCC. How HPV confers a less aggressive phenotype, however, remains undefined. We demo...

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Detalles Bibliográficos
Autores principales: Antonioli, Manuela, Pagni, Benedetta, Vescovo, Tiziana, Ellis, Rob, Cosway, Benjamin, Rollo, Francesca, Bordoni, Veronica, Agrati, Chiara, Labus, Marie, Covello, Renato, Benevolo, Maria, Ippolito, Giuseppe, Robinson, Max, Piacentini, Mauro, Lovat, Penny, Fimia, Gian Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526016/
https://www.ncbi.nlm.nih.gov/pubmed/33172332
http://dx.doi.org/10.1080/15548627.2020.1847444

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