A high-throughput screening identifies ZNF418 as a novel regulator of the ubiquitin-proteasome system and autophagy-lysosomal pathway

The ubiquitin-proteasome system (UPS) and autophagy-lysosomal pathway (ALP) are two major protein degradation pathways in eukaryotic cells. Initially considered as two independent pathways, there is emerging evidence that they can work in concert. As alterations of UPS and ALP function can contribut...

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Detalles Bibliográficos
Autores principales: Singh, Sonia R, Meyer-Jens, Moritz, Alizoti, Erda, Bacon, W Clark, Davis, Gregory, Osinska, Hanna, Gulick, James, Reischmann-Düsener, Silke, Orthey, Ellen, McLendon, Patrick M, Molkentin, Jeffery D, Schlossarek, Saskia, Robbins, Jeffrey, Carrier, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526018/
https://www.ncbi.nlm.nih.gov/pubmed/33249983
http://dx.doi.org/10.1080/15548627.2020.1856493

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