A single mutation in the cis-acting replication element identified within the EV-A71 2C-coding region causes defects in virus production in cell culture

Enterovirus A71 (EV-A71) can cause hand, foot and mouth disease with neurological and systemic complications, most frequently affecting children and infants. We describe a cis-acting replication element (cre) with a conserved stem-loop structure within the EV-A71 2C-coding region. By site-directed m...

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Detalles Bibliográficos
Autores principales: Xi, Juemin, Ma, Chunxia, Wei, Zhizhong, Yin, Bin, Zhao, Siwen, Quan, Wenqi, Yang, Jing, Yuan, Jiangang, Qiang, Boqin, Ye, Fei, Peng, Xiaozhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526025/
https://www.ncbi.nlm.nih.gov/pubmed/34511027
http://dx.doi.org/10.1080/22221751.2021.1977590

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