Cargando…

Dengue: A Neglected Disease of Concern

Background Dengue fever, more prevalent in Asia, is a highly neglected vector-borne disease. It has a varied presentation ranging from common fever to atypical presentation as encephalitis. This study aimed to analyze the demographic and clinical profile of dengue patients admitted to a tertiary car...

Descripción completa

Detalles Bibliográficos
Autores principales: Jisamerin, Joy, Mohamedkalifa, Abdulmuthalif, Gaur, Archana, Geetha, Jeganathan, Sakthivadivel, Varatharajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526076/
https://www.ncbi.nlm.nih.gov/pubmed/34692260
http://dx.doi.org/10.7759/cureus.18500
_version_ 1784585801894461440
author Jisamerin, Joy
Mohamedkalifa, Abdulmuthalif
Gaur, Archana
Geetha, Jeganathan
Sakthivadivel, Varatharajan
author_facet Jisamerin, Joy
Mohamedkalifa, Abdulmuthalif
Gaur, Archana
Geetha, Jeganathan
Sakthivadivel, Varatharajan
author_sort Jisamerin, Joy
collection PubMed
description Background Dengue fever, more prevalent in Asia, is a highly neglected vector-borne disease. It has a varied presentation ranging from common fever to atypical presentation as encephalitis. This study aimed to analyze the demographic and clinical profile of dengue patients admitted to a tertiary care center in Tamilnadu. Methodology This retrospective study was performed by collecting patient data from the medical records department for the years 2012 to 2014. A total of 150 patients with 50 patients from each year were selected. The patient’s demographic data, clinical profile, management, and outcome were noted. Patients were divided into three groups as per the World Health Organization’s 2009 classification. Results Most dengue cases occurred from October to December (70.7%). The number of male and female patients was almost equal (77 [51.3%] and 73 [48.7%], respectively). The middle-aged group (21-40 years) was commonly affected (54%). The mean age was 29 ± 13.20 years. Fever was the most common symptom (100%), followed by lethargy (81.3%) and myalgia (60.7%). Overall, 10% of patients had comorbidities such as diabetes, hypertension, and ischemic heart disease. Moreover, 22.7% of patients had dengue with warning signs, and severe dengue was seen in 19.3% of patients. A significant difference was noted in the total count, comorbidities, serositis, and the duration of hospitalization between the groups. No mortality was recorded in the study population. Conclusions Dengue is very common in the middle-aged group. Patients with severe dengue had significant leucopenia, several comorbidities, and serositis. The mortality can be reduced to <1% and even zero in severe dengue according to our study with close monitoring and supportive care.
format Online
Article
Text
id pubmed-8526076
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-85260762021-10-22 Dengue: A Neglected Disease of Concern Jisamerin, Joy Mohamedkalifa, Abdulmuthalif Gaur, Archana Geetha, Jeganathan Sakthivadivel, Varatharajan Cureus Internal Medicine Background Dengue fever, more prevalent in Asia, is a highly neglected vector-borne disease. It has a varied presentation ranging from common fever to atypical presentation as encephalitis. This study aimed to analyze the demographic and clinical profile of dengue patients admitted to a tertiary care center in Tamilnadu. Methodology This retrospective study was performed by collecting patient data from the medical records department for the years 2012 to 2014. A total of 150 patients with 50 patients from each year were selected. The patient’s demographic data, clinical profile, management, and outcome were noted. Patients were divided into three groups as per the World Health Organization’s 2009 classification. Results Most dengue cases occurred from October to December (70.7%). The number of male and female patients was almost equal (77 [51.3%] and 73 [48.7%], respectively). The middle-aged group (21-40 years) was commonly affected (54%). The mean age was 29 ± 13.20 years. Fever was the most common symptom (100%), followed by lethargy (81.3%) and myalgia (60.7%). Overall, 10% of patients had comorbidities such as diabetes, hypertension, and ischemic heart disease. Moreover, 22.7% of patients had dengue with warning signs, and severe dengue was seen in 19.3% of patients. A significant difference was noted in the total count, comorbidities, serositis, and the duration of hospitalization between the groups. No mortality was recorded in the study population. Conclusions Dengue is very common in the middle-aged group. Patients with severe dengue had significant leucopenia, several comorbidities, and serositis. The mortality can be reduced to <1% and even zero in severe dengue according to our study with close monitoring and supportive care. Cureus 2021-10-05 /pmc/articles/PMC8526076/ /pubmed/34692260 http://dx.doi.org/10.7759/cureus.18500 Text en Copyright © 2021, Jisamerin et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Jisamerin, Joy
Mohamedkalifa, Abdulmuthalif
Gaur, Archana
Geetha, Jeganathan
Sakthivadivel, Varatharajan
Dengue: A Neglected Disease of Concern
title Dengue: A Neglected Disease of Concern
title_full Dengue: A Neglected Disease of Concern
title_fullStr Dengue: A Neglected Disease of Concern
title_full_unstemmed Dengue: A Neglected Disease of Concern
title_short Dengue: A Neglected Disease of Concern
title_sort dengue: a neglected disease of concern
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526076/
https://www.ncbi.nlm.nih.gov/pubmed/34692260
http://dx.doi.org/10.7759/cureus.18500
work_keys_str_mv AT jisamerinjoy dengueaneglecteddiseaseofconcern
AT mohamedkalifaabdulmuthalif dengueaneglecteddiseaseofconcern
AT gaurarchana dengueaneglecteddiseaseofconcern
AT geethajeganathan dengueaneglecteddiseaseofconcern
AT sakthivadivelvaratharajan dengueaneglecteddiseaseofconcern