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Metformin alleviates stress-induced cellular senescence of aging human adipose stromal cells and the ensuing adipocyte dysfunction

Aging is associated with central fat redistribution and insulin resistance. To identify age-related adipose features, we evaluated the senescence and adipogenic potential of adipose-derived stromal cells (ASCs) from abdominal subcutaneous fat obtained from healthy normal-weight young (<25 years)...

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Detalles Bibliográficos
Autores principales: Le Pelletier, Laura, Mantecon, Matthieu, Gorwood, Jennifer, Auclair, Martine, Foresti, Roberta, Motterlini, Roberto, Laforge, Mireille, Atlan, Michael, Fève, Bruno, Capeau, Jacqueline, Lagathu, Claire, Bereziat, Veronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526089/
https://www.ncbi.nlm.nih.gov/pubmed/34544550
http://dx.doi.org/10.7554/eLife.62635

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