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Metformin alleviates stress-induced cellular senescence of aging human adipose stromal cells and the ensuing adipocyte dysfunction
Aging is associated with central fat redistribution and insulin resistance. To identify age-related adipose features, we evaluated the senescence and adipogenic potential of adipose-derived stromal cells (ASCs) from abdominal subcutaneous fat obtained from healthy normal-weight young (<25 years)...
Autores principales: | Le Pelletier, Laura, Mantecon, Matthieu, Gorwood, Jennifer, Auclair, Martine, Foresti, Roberta, Motterlini, Roberto, Laforge, Mireille, Atlan, Michael, Fève, Bruno, Capeau, Jacqueline, Lagathu, Claire, Bereziat, Veronique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526089/ https://www.ncbi.nlm.nih.gov/pubmed/34544550 http://dx.doi.org/10.7554/eLife.62635 |
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