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Preservation of the Aortic Root During Type A Aortic Dissection Surgery: An Effective Strategy?

Background  Management of the aortic root during acute Type A aortic dissection (TAAD) repair remains controversial in term of long-term evolution and reoperation. The aim of this study was to assess the long-term outcomes of the aortic root after conservative management during primary surgery. Meth...

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Autores principales: Dang Van, Simon, Laribi, Jihed, Pinaud, Frédéric, Binuani, Patrice, Willoteaux, Serge, Baufreton, Christophe, Fouquet, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical Publishers, Inc. 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526144/
https://www.ncbi.nlm.nih.gov/pubmed/34619800
http://dx.doi.org/10.1055/s-0041-1725074
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author Dang Van, Simon
Laribi, Jihed
Pinaud, Frédéric
Binuani, Patrice
Willoteaux, Serge
Baufreton, Christophe
Fouquet, Olivier
author_facet Dang Van, Simon
Laribi, Jihed
Pinaud, Frédéric
Binuani, Patrice
Willoteaux, Serge
Baufreton, Christophe
Fouquet, Olivier
author_sort Dang Van, Simon
collection PubMed
description Background  Management of the aortic root during acute Type A aortic dissection (TAAD) repair remains controversial in term of long-term evolution and reoperation. The aim of this study was to assess the long-term outcomes of the aortic root after conservative management during primary surgery. Methods  One hundred sixty-four consecutive patients were included in this monocentric retrospective study. The primary endpoint was reoperation on the aortic root during long-term follow-up. Forty-six patients had aortic root replacement (ARR) and 118 had supracoronary aortic replacement (SCR). The 10-year survival, occurrence of significant aortic regurgitation, and radiologic aortic root dilatation in each group were assessed during follow-up. Results  Patients from ARR group were younger than those from SCR group ( p  < 0.0001). Median follow-ups of ARR group and SCR group are 4.4 (interquartile range [IR]: 2.6–8.3) and 6.15 (IR: 2.8–10.53) years, respectively. Reoperation of the aortic root during long-term follow-up was similar in both groups (ARR group: 5.1%, SCR group: 3.3%, p  = 0.636). The 10-year survivals of ARR and SCR groups were 64.8 ± 12.3% and 46.3 ± 5.8% ( p  = 0.012), respectively. Long-term significant aortic regurgitation occurred in one patient (1.7%) and seven patients (7.6%) of the ARR and SCR groups ( p  = 0.176), respectively. Radiologic aortic root diameters in the SCR group were similar between postoperative period and follow-up studies ( p  = 0.58). Reoperation on the distal aorta ( p  = 0.012) and patent radiologic false lumen of the descending aorta ( p  = 0.043) were independent risk factors of late death. Conclusion  SCR is an effective technique for primary TAAD surgery and does not increase the rate of late reoperation on the aortic root.
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spelling pubmed-85261442021-10-21 Preservation of the Aortic Root During Type A Aortic Dissection Surgery: An Effective Strategy? Dang Van, Simon Laribi, Jihed Pinaud, Frédéric Binuani, Patrice Willoteaux, Serge Baufreton, Christophe Fouquet, Olivier Aorta (Stamford) Background  Management of the aortic root during acute Type A aortic dissection (TAAD) repair remains controversial in term of long-term evolution and reoperation. The aim of this study was to assess the long-term outcomes of the aortic root after conservative management during primary surgery. Methods  One hundred sixty-four consecutive patients were included in this monocentric retrospective study. The primary endpoint was reoperation on the aortic root during long-term follow-up. Forty-six patients had aortic root replacement (ARR) and 118 had supracoronary aortic replacement (SCR). The 10-year survival, occurrence of significant aortic regurgitation, and radiologic aortic root dilatation in each group were assessed during follow-up. Results  Patients from ARR group were younger than those from SCR group ( p  < 0.0001). Median follow-ups of ARR group and SCR group are 4.4 (interquartile range [IR]: 2.6–8.3) and 6.15 (IR: 2.8–10.53) years, respectively. Reoperation of the aortic root during long-term follow-up was similar in both groups (ARR group: 5.1%, SCR group: 3.3%, p  = 0.636). The 10-year survivals of ARR and SCR groups were 64.8 ± 12.3% and 46.3 ± 5.8% ( p  = 0.012), respectively. Long-term significant aortic regurgitation occurred in one patient (1.7%) and seven patients (7.6%) of the ARR and SCR groups ( p  = 0.176), respectively. Radiologic aortic root diameters in the SCR group were similar between postoperative period and follow-up studies ( p  = 0.58). Reoperation on the distal aorta ( p  = 0.012) and patent radiologic false lumen of the descending aorta ( p  = 0.043) were independent risk factors of late death. Conclusion  SCR is an effective technique for primary TAAD surgery and does not increase the rate of late reoperation on the aortic root. Thieme Medical Publishers, Inc. 2021-10-07 /pmc/articles/PMC8526144/ /pubmed/34619800 http://dx.doi.org/10.1055/s-0041-1725074 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ ) https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Dang Van, Simon
Laribi, Jihed
Pinaud, Frédéric
Binuani, Patrice
Willoteaux, Serge
Baufreton, Christophe
Fouquet, Olivier
Preservation of the Aortic Root During Type A Aortic Dissection Surgery: An Effective Strategy?
title Preservation of the Aortic Root During Type A Aortic Dissection Surgery: An Effective Strategy?
title_full Preservation of the Aortic Root During Type A Aortic Dissection Surgery: An Effective Strategy?
title_fullStr Preservation of the Aortic Root During Type A Aortic Dissection Surgery: An Effective Strategy?
title_full_unstemmed Preservation of the Aortic Root During Type A Aortic Dissection Surgery: An Effective Strategy?
title_short Preservation of the Aortic Root During Type A Aortic Dissection Surgery: An Effective Strategy?
title_sort preservation of the aortic root during type a aortic dissection surgery: an effective strategy?
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526144/
https://www.ncbi.nlm.nih.gov/pubmed/34619800
http://dx.doi.org/10.1055/s-0041-1725074
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