Cargando…

A Monoiodotyrosine Challenge Test in a Parkinson’s Disease Model

Early (preclinical) diagnosis of Parkinson’s disease (PD) is a major challenge in modern neuroscience. The objective of this study was to experimentally evaluate a diagnostic challenge test with monoiodotyrosine (MIT), an endogenous inhibitor of tyrosine hydroxylase. Striatal dopamine was shown to d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, A. R., Pavlova, E. N., Blokhin, V. E., Bogdanov, V. V., Ugrumov, M. V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	A.I. Gordeyev 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526187/ https://www.ncbi.nlm.nih.gov/pubmed/34707902 http://dx.doi.org/10.32607/actanaturae.11399

Ejemplares similares

The Sphingolipid Asset Is Altered in the Nigrostriatal System of Mice Models of Parkinson’s Disease
por: Blokhin, Victor, et al.
Publicado: (2022)

A Pilot Study of Changes in the Level of Catecholamines and the Activity of α-2-Macroglobulin in the Tear Fluid of Patients with Parkinson’s Disease and Parkinsonian Mice
por: Bogdanov, Vsevolod, et al.
Publicado: (2021)

Compensatory Processes in Striatal Neurons Expressing the Tyrosine Hydroxylase Gene in Transgenic Mice in a Model of Parkinson’s Disease
por: Troshev, Dmitry, et al.
Publicado: (2023)

The Periventricular Nucleus as a Brain Center Containing Dopaminergic Neurons and Neurons Expressing Individual Enzymes of Dopamine Synthesis
por: Ugrumov, Michael V., et al.
Publicado: (2022)

Modeling of the Progressive Degradation of the Nigrostriatal Dopaminergic System in Mice to Study the Mechanisms of Neurodegeneration and Neuroplasticity in Parkinson’s Disease
por: Kolacheva, Anna, et al.
Publicado: (2022)

Searching for Biomarkers in the Blood of Patients at Risk of Developing Parkinson’s Disease at the Prodromal Stage
por: Katunina, Elena A., et al.
Publicado: (2023)

The Gene Expression of Proteins Involved in Intercellular Signaling and Neurodegeneration in the Substantia Nigra in a Mouse Subchronic Model of Parkinson’s Disease
por: Kolacheva, Anna, et al.
Publicado: (2023)

LUHMES Cells: Phenotype Refinement and Development of an MPP(+)-Based Test System for Screening Antiparkinsonian Drugs
por: Beliakov, Sergei V., et al.
Publicado: (2023)

Changes in Tyrosine Hydroxylase Activity and Dopamine Synthesis in the Nigrostriatal System of Mice in an Acute Model of Parkinson’s Disease as a Manifestation of Neurodegeneration and Neuroplasticity
por: Kolacheva, Anna, et al.
Publicado: (2022)

A Mouse Model of Nigrostriatal Dopaminergic Axonal Degeneration As a Tool for Testing Neuroprotectors
por: Kolacheva, A. A., et al.
Publicado: (2021)

Tear Fluid Catecholamines As Biomarkers of the Parkinson’s Disease: A Clinical and Experimental Study
por: Kim, A. R., et al.
Publicado: (2019)

Molecular Mechanisms and Clinical Manifestations of Catecholamine Dysfunction in the Eye in Parkinson’s Disease As a Basis for Developing Early Diagnosis
por: Pavlenko, T. A., et al.
Publicado: (2020)

A New Method for the Visualization of Living Dopaminergic Neurons and Prospects for Using It to Develop Targeted Drug Delivery to These Cells
por: Blokhin, Victor, et al.
Publicado: (2022)

Biochemical and Functional Changes in the Eye As a Manifestation of Systemic Degeneration of the Nervous System in Parkinsonism
por: Kim, A. R., et al.
Publicado: (2018)

Development of early diagnosis of Parkinson's disease: Illusion or reality?
por: Ugrumov, Michael
Publicado: (2020)

A Comparative Analysis of CSF and the Blood Levels of Monoamines As Neurohormones in Rats during Ontogenesis
por: Murtazina, A. R., et al.
Publicado: (2021)

Isolation of living dopaminergic neurons labeled with a fluorescent ligand of the dopamine transporter from mouse substantia nigra as a new tool for basic and applied research
por: Troshev, Dmitry, et al.
Publicado: (2022)

Expression Analysis of Genes Involved in Transport Processes in Mice with MPTP-Induced Model of Parkinson’s Disease
por: Rudenok, Margarita M., et al.
Publicado: (2022)

Striatal Neurons Partially Expressing a Dopaminergic Phenotype: Functional Significance and Regulation
por: Troshev, Dmitry, et al.
Publicado: (2022)

Effects of striatal transplantation of cells transfected with GDNF gene without pre- and pro-regions in mouse model of Parkinson’s disease
por: Revishchin, A., et al.
Publicado: (2016)

Development of the Periventricular Nucleus as a Brain Center, Containing Dopaminergic Neurons and Neurons Expressing Individual Enzymes of Dopamine Synthesis
por: Pronina, Tatiana, et al.
Publicado: (2022)

Seasonal dynamics of a complex cheilostome bryozoan symbiosis: vertical transfer challenged
por: Bogdanov, E. A., et al.
Publicado: (2023)

Current Challenges Towards the Development of a Blood Test for Parkinson’s Disease
por: Santiago, Jose A., et al.
Publicado: (2014)

The Effect of Dopamine Secreted by the Brain into the Systemic Circulation on Prolactin Synthesis by the Pituitary gland in Ontogenesis
por: Nikishina, Yu.O., et al.
Publicado: (2016)

Dopamine Neuron Challenge Test for early detection of Parkinson’s disease
por: Zhou, Jingheng, et al.
Publicado: (2021)

Biochemical Characteristics of iPSC-Derived Dopaminergic Neurons from N370S GBA Variant Carriers with and without Parkinson’s Disease
por: Grigor’eva, Elena V., et al.
Publicado: (2023)

VCP expression decrease as a biomarker of preclinical and early clinical stages of Parkinson’s disease
por: Alieva, Anelya, et al.
Publicado: (2020)

Neuroprotection by immunomodulatory agents in animal models of Parkinson’s disease
por: Martinez, Bridget, et al.
Publicado: (2018)

People with Parkinson’s as Partners for the Journal of Parkinson’s Disease
por: McFarthing, Kevin, et al.
Publicado: (2023)

Parkinson’s Disease: Available Clinical and Promising Omics Tests for Diagnostics, Disease Risk Assessment, and Pharmacotherapy Personalization
por: Trifonova, Oxana P., et al.
Publicado: (2020)

Tyrosine Hydroxylase Expression in Differentiating Neurons of the Rat Arcuate Nucleus: Stimulatory Influence of Serotonin Afferents
por: Melnikova, Viktoria I., et al.
Publicado: (2001)

Behavioral Tests in Neurotoxin-Induced Animal Models of Parkinson’s Disease
por: Prasad, E. Maruthi, et al.
Publicado: (2020)

Mitochondria and Quality Control Defects in a Mouse Model of Gaucher Disease—Links to Parkinson’s Disease
por: Osellame, Laura D., et al.
Publicado: (2013)

Evaluation of the cross-sections of threshold reactions leading to the production of long-lived radionuclides during irradiation of steels by thermonuclear spectrum neutrons
por: Blokhin, A I, et al.
Publicado: (2001)

Institutional Transformations of Russia’s Housing Construction Sector in 2020
por: Blokhin, A. A., et al.
Publicado: (2021)

Schrimer test in Parkinson's disease.
por: Kwon, O. Y., et al.
Publicado: (1994)

Restoration of intestinal function in an MPTP model of Parkinson’s Disease
por: Ellett, L. J., et al.
Publicado: (2016)

Neuroprotective effects of linagliptin in a rotenone-induced rat model of Parkinson's disease
por: Abhangi, Kinjal V, et al.
Publicado: (2022)

A.S. Pushkin v portretaj = Pushkin : a gallery of portraits, [2] /
por: Pavlova, E. V. (Ekaterina Vsevolodovna)
Publicado: (1983)

A.S. Pushkin v portretaj = Pushkin : a gallery of portraits, [1] /
por: Pavlova, E. V. (Ekaterina Vsevolodovna)
Publicado: (1983)

Cannot write session to /tmp/vufind_sessions/sess_sf04frluc2agigtq6dev6t8qnh