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Role of SIRT1 in Hepatic Encephalopathy: In Vivo and In Vitro Studies Focusing on the NLRP3 Inflammasome

Hepatic encephalopathy (HE) is a neuropsychiatric disorder resulting from acute or chronic liver failure. This study is aimed at investigating the therapeutic effects and mechanisms of SIRT1 in thioacetamide- (TAA-) induced rat HE models. A selective activator (CAY10602) and inhibitor (EX527) of SIR...

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Detalles Bibliográficos
Autores principales:	Jiao, Fangzhou, Wang, Yao, Chen, Qian, Cao, Pan, Shi, Chunxia, Pei, Maohua, Wang, Luwen, Gong, Zuojiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526203/ https://www.ncbi.nlm.nih.gov/pubmed/34676022 http://dx.doi.org/10.1155/2021/5522708

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