Cargando…

Epidemiological Features and Predictors of Mortality in Patients with COVID-19 with and without Underlying Hypertension

BACKGROUNDS: Individuals with hypertension are at higher risk of COVID-19 infection and related mortality. This study was carried out to assess the epidemiological features and predictors of mortality in patients with COVID-19 with hypertension. METHODS: In this retrospective study, the epidemiologi...

Descripción completa

Detalles Bibliográficos
Autores principales: Moftakhar, Leila, Piraee, Elahe, Mohammadi Abnavi, Mohammad, Moftakhar, Parisa, Azarbakhsh, Habibollah, Valipour, Aliasghar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526257/
https://www.ncbi.nlm.nih.gov/pubmed/34676114
http://dx.doi.org/10.1155/2021/7427500
_version_ 1784585844706770944
author Moftakhar, Leila
Piraee, Elahe
Mohammadi Abnavi, Mohammad
Moftakhar, Parisa
Azarbakhsh, Habibollah
Valipour, Aliasghar
author_facet Moftakhar, Leila
Piraee, Elahe
Mohammadi Abnavi, Mohammad
Moftakhar, Parisa
Azarbakhsh, Habibollah
Valipour, Aliasghar
author_sort Moftakhar, Leila
collection PubMed
description BACKGROUNDS: Individuals with hypertension are at higher risk of COVID-19 infection and related mortality. This study was carried out to assess the epidemiological features and predictors of mortality in patients with COVID-19 with hypertension. METHODS: In this retrospective study, the epidemiological characteristics of two groups of patients with COVID-19 with hypertension (1927) and without hypertension (39030) were compared. Chi-square test was applied to evaluate the differences between qualitative variables in two study groups. Logistic regression was also used to determine predictors of mortality in patients with COVID-19 and in patients with COVID-19 with hypertension. RESULTS: The prevalence of hypertension in patients with COVID-19 was 4.7%, and 24.37% of COVID-19 related deaths occurred in these individuals. The average age of hypertension and nonhypertension patients was 61 and 37 years, respectively. Fever, cough, headache, anorexia, fatigue, and comorbid diseases, such as cardiovascular disease, chronic lung and kidney disease, diabetes, immunodeficiency disease, and thyroid disease, were significantly more frequent in people with hypertension than those without hypertension. The chances of mortality in patient with COVID-19 were 1.8 times higher in individuals with dyspnea, 1.25 in individuals with fever, 1.33 in individuals with cough, 3.6 in patients with hypertension, 2.21 in diabetics, and 2.2 in individuals with cardiovascular disease. Also, individuals with COVID-19 with hypertension that had dyspnea, immunodeficiency, and cardiovascular disease were at higher risk of mortality. CONCLUSION: Hypertension is a serious threat to patients with COVID-19. Therefore, in order to control these patients more precisely and reduce mortality in them, it is extremely important to develop prevention and treatment strategies.
format Online
Article
Text
id pubmed-8526257
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-85262572021-10-20 Epidemiological Features and Predictors of Mortality in Patients with COVID-19 with and without Underlying Hypertension Moftakhar, Leila Piraee, Elahe Mohammadi Abnavi, Mohammad Moftakhar, Parisa Azarbakhsh, Habibollah Valipour, Aliasghar Int J Hypertens Research Article BACKGROUNDS: Individuals with hypertension are at higher risk of COVID-19 infection and related mortality. This study was carried out to assess the epidemiological features and predictors of mortality in patients with COVID-19 with hypertension. METHODS: In this retrospective study, the epidemiological characteristics of two groups of patients with COVID-19 with hypertension (1927) and without hypertension (39030) were compared. Chi-square test was applied to evaluate the differences between qualitative variables in two study groups. Logistic regression was also used to determine predictors of mortality in patients with COVID-19 and in patients with COVID-19 with hypertension. RESULTS: The prevalence of hypertension in patients with COVID-19 was 4.7%, and 24.37% of COVID-19 related deaths occurred in these individuals. The average age of hypertension and nonhypertension patients was 61 and 37 years, respectively. Fever, cough, headache, anorexia, fatigue, and comorbid diseases, such as cardiovascular disease, chronic lung and kidney disease, diabetes, immunodeficiency disease, and thyroid disease, were significantly more frequent in people with hypertension than those without hypertension. The chances of mortality in patient with COVID-19 were 1.8 times higher in individuals with dyspnea, 1.25 in individuals with fever, 1.33 in individuals with cough, 3.6 in patients with hypertension, 2.21 in diabetics, and 2.2 in individuals with cardiovascular disease. Also, individuals with COVID-19 with hypertension that had dyspnea, immunodeficiency, and cardiovascular disease were at higher risk of mortality. CONCLUSION: Hypertension is a serious threat to patients with COVID-19. Therefore, in order to control these patients more precisely and reduce mortality in them, it is extremely important to develop prevention and treatment strategies. Hindawi 2021-10-19 /pmc/articles/PMC8526257/ /pubmed/34676114 http://dx.doi.org/10.1155/2021/7427500 Text en Copyright © 2021 Leila Moftakhar et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Moftakhar, Leila
Piraee, Elahe
Mohammadi Abnavi, Mohammad
Moftakhar, Parisa
Azarbakhsh, Habibollah
Valipour, Aliasghar
Epidemiological Features and Predictors of Mortality in Patients with COVID-19 with and without Underlying Hypertension
title Epidemiological Features and Predictors of Mortality in Patients with COVID-19 with and without Underlying Hypertension
title_full Epidemiological Features and Predictors of Mortality in Patients with COVID-19 with and without Underlying Hypertension
title_fullStr Epidemiological Features and Predictors of Mortality in Patients with COVID-19 with and without Underlying Hypertension
title_full_unstemmed Epidemiological Features and Predictors of Mortality in Patients with COVID-19 with and without Underlying Hypertension
title_short Epidemiological Features and Predictors of Mortality in Patients with COVID-19 with and without Underlying Hypertension
title_sort epidemiological features and predictors of mortality in patients with covid-19 with and without underlying hypertension
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526257/
https://www.ncbi.nlm.nih.gov/pubmed/34676114
http://dx.doi.org/10.1155/2021/7427500
work_keys_str_mv AT moftakharleila epidemiologicalfeaturesandpredictorsofmortalityinpatientswithcovid19withandwithoutunderlyinghypertension
AT piraeeelahe epidemiologicalfeaturesandpredictorsofmortalityinpatientswithcovid19withandwithoutunderlyinghypertension
AT mohammadiabnavimohammad epidemiologicalfeaturesandpredictorsofmortalityinpatientswithcovid19withandwithoutunderlyinghypertension
AT moftakharparisa epidemiologicalfeaturesandpredictorsofmortalityinpatientswithcovid19withandwithoutunderlyinghypertension
AT azarbakhshhabibollah epidemiologicalfeaturesandpredictorsofmortalityinpatientswithcovid19withandwithoutunderlyinghypertension
AT valipouraliasghar epidemiologicalfeaturesandpredictorsofmortalityinpatientswithcovid19withandwithoutunderlyinghypertension