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Safety and efficiency modifications of SIV-based integrase-defective lentiviral vectors for immunization

Integrase-defective lentiviral vectors (IDLVs) represent an attractive platform for vaccine development as a result of the ability to induce persistent humoral- and cellular-mediated immune responses against the encoded transgene. Compared with the parental integrating vector, the main advantages fo...

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Detalles Bibliográficos
Autores principales: Bona, Roberta, Michelini, Zuleika, Mazzei, Chiara, Gallinaro, Alessandra, Canitano, Andrea, Borghi, Martina, Vescio, Maria Fenicia, Di Virgilio, Antonio, Pirillo, Maria Franca, Klotman, Mary E., Negri, Donatella, Cara, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526422/
https://www.ncbi.nlm.nih.gov/pubmed/34729374
http://dx.doi.org/10.1016/j.omtm.2021.09.011