Cargando…
Safety and efficiency modifications of SIV-based integrase-defective lentiviral vectors for immunization
Integrase-defective lentiviral vectors (IDLVs) represent an attractive platform for vaccine development as a result of the ability to induce persistent humoral- and cellular-mediated immune responses against the encoded transgene. Compared with the parental integrating vector, the main advantages fo...
Autores principales: | Bona, Roberta, Michelini, Zuleika, Mazzei, Chiara, Gallinaro, Alessandra, Canitano, Andrea, Borghi, Martina, Vescio, Maria Fenicia, Di Virgilio, Antonio, Pirillo, Maria Franca, Klotman, Mary E., Negri, Donatella, Cara, Andrea |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526422/ https://www.ncbi.nlm.nih.gov/pubmed/34729374 http://dx.doi.org/10.1016/j.omtm.2021.09.011 |
Ejemplares similares
-
Integrase-Defective Lentiviral Vector Is an Efficient Vaccine Platform for Cancer Immunotherapy
por: Morante, Valeria, et al.
Publicado: (2021) -
Development and Preclinical Evaluation of an Integrase Defective Lentiviral Vector Vaccine Expressing the HIVACAT T Cell Immunogen in Mice
por: Gallinaro, Alessandra, et al.
Publicado: (2020) -
Integrase Defective Lentiviral Vector as a Vaccine Platform for Delivering Influenza Antigens
por: Gallinaro, Alessandra, et al.
Publicado: (2018) -
Persistent immunogenicity of integrase defective lentiviral vectors delivering membrane-tethered native-like HIV-1 envelope trimers
por: Gallinaro, Alessandra, et al.
Publicado: (2022) -
Optimization of Mucosal Responses after Intramuscular Immunization with Integrase Defective Lentiviral Vector
por: Rossi, Alessandra, et al.
Publicado: (2014)