Therapeutically targeting oncogenic CRCs facilitates induced differentiation of NB by RA and the BET bromodomain inhibitor

Retinoic acids (RAs) are the most successful therapeutics for cancer differentiation therapy used in high-risk neuroblastoma (NB) maintenance therapy but are limited in effectiveness. This study identifies a strategy for improving efficacy through disruption of cancer cell identity via BET inhibitor...

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Detalles Bibliográficos
Autores principales: Alleboina, Satyanarayana, Aljouda, Nour, Miller, Mellessa, Freeman, Kevin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526497/
https://www.ncbi.nlm.nih.gov/pubmed/34729395
http://dx.doi.org/10.1016/j.omto.2021.09.004

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