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Upregulation of CD22 by Chidamide promotes CAR T cells functionality
Treatment failure or relapse due to tumor escape caused by reduction in target antigen expression has become a challenge in the field of CART therapy. Target antigen density is closely related to the effectiveness of CART therapy, and reduced or lost target antigen expression limits the efficacy of...
Autores principales: | Yang, Xin, Yu, Qiuxia, Xu, Hao, Zhou, Jianfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526578/ https://www.ncbi.nlm.nih.gov/pubmed/34667217 http://dx.doi.org/10.1038/s41598-021-00227-4 |
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