Cargando…

Economical droplet-based microfluidic production of [(18)F]FET and [(18)F]Florbetaben suitable for human use

Current equipment and methods for preparation of radiopharmaceuticals for positron emission tomography (PET) are expensive and best suited for large-scale multi-doses batches. Microfluidic radiosynthesizers have been shown to provide an economic approach to synthesize these compounds in smaller quan...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lisova, Ksenia, Wang, Jia, Hajagos, Tibor Jacob, Lu, Yingqing, Hsiao, Alexander, Elizarov, Arkadij, van Dam, R. Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526601/ https://www.ncbi.nlm.nih.gov/pubmed/34667246 http://dx.doi.org/10.1038/s41598-021-99111-4

Ejemplares similares

A simple and efficient automated microvolume radiosynthesis of [(18)F]Florbetaben
por: Lisova, Ksenia, et al.
Publicado: (2020)

Rapid, efficient, and economical synthesis of PET tracers in a droplet microreactor: application to O-(2-[(18)F]fluoroethyl)-L-tyrosine ([(18)F]FET)
por: Lisova, Ksenia, et al.
Publicado: (2019)

Comparison Between (18)F-Florapronol and (18)F-Florbetaben Imaging in Patients With Cognitive Impairment
por: Baik, Kyoungwon, et al.
Publicado: (2023)

Optimized dual-time-window protocols for quantitative [(18)F]flutemetamol and [(18)F]florbetaben PET studies
por: Heeman, Fiona, et al.
Publicado: (2019)

Clinical Relevance of [(18)F]Florbetaben and [(18)F]FDG PET/CT Imaging on the Management of Patients with Dementia
por: Librizzi, Damiano, et al.
Publicado: (2021)

(18)F-florbetaben Aβ imaging in mild cognitive impairment
por: Ong, Kevin, et al.
Publicado: (2013)

Amyloid PET imaging in multiple sclerosis: an (18)F-florbetaben study
por: Matías-Guiu, Jordi A., et al.
Publicado: (2015)

(18)F-Florbetaben PET beta-amyloid binding expressed in Centiloids
por: Rowe, Christopher C., et al.
Publicado: (2017)

Early detection of amyloid load using (18)F-florbetaben PET
por: Bullich, Santiago, et al.
Publicado: (2021)

Appropriate reference region selection of (18)F-florbetaben and (18)F-flutemetamol beta-amyloid PET expressed in Centiloid
por: Cho, Soo Hyun, et al.
Publicado: (2020)

Simulating the effect of cerebral blood flow changes on regional quantification of [(18)F]flutemetamol and [(18)F]florbetaben studies
por: Heeman, Fiona, et al.
Publicado: (2020)

Concordance in detecting amyloid positivity between (18)F-florbetaben and (18)F-flutemetamol amyloid PET using quantitative and qualitative assessments
por: Cho, Soo Hyun, et al.
Publicado: (2020)

Evaluation of early-phase [(18)F]-florbetaben PET acquisition in clinical routine cases
por: Daerr, Sonja, et al.
Publicado: (2016)

(18)F-florbetaben whole-body PET/MRI for evaluation of systemic amyloid deposition
por: Baratto, Lucia, et al.
Publicado: (2018)

Feasibility of in vivo (18)F-florbetaben PET/MR imaging of human carotid amyloid-β
por: Bucerius, Jan, et al.
Publicado: (2017)

(18)F-florbetaben positron emission tomography detects cardiac involvement in systemic AA amyloidosis
por: Papathanasiou, Maria, et al.
Publicado: (2020)

Patterns of Focal Amyloid Deposition Using (18)F-Florbetaben PET in Patients with Cognitive Impairment
por: Chung, Sung-eun, et al.
Publicado: (2022)

Alzheimer’s Disease Prediction Using Attention Mechanism with Dual-Phase (18)F-Florbetaben Images
por: Kang, Hyeon, et al.
Publicado: (2022)

(18)F-FET and (18)F-FCH uptake in human glioblastoma T98G cell lines
por: Persico, Marco Giovanni, et al.
Publicado: (2016)

Assessment of brain beta-amyloid deposition in transgenic mouse models of Alzheimer’s disease with PET imaging agents (18)F-flutemetamol and (18)F-florbetaben
por: Son, Hye Joo, et al.
Publicado: (2018)

Author Correction: Concordance in detecting amyloid positivity between (18)F-florbetaben and (18)F-flutemetamol amyloid PET using quantitative and qualitative assessments
por: Cho, Soo Hyun, et al.
Publicado: (2021)

Effects of Photons Irradiation on (18)F-FET and (18)F-DOPA Uptake by T98G Glioblastoma Cells
por: Pasi, Francesca, et al.
Publicado: (2020)

Evaluation of factors influencing (18)F-FET uptake in the brain
por: Verger, Antoine, et al.
Publicado: (2017)

The Impact of Amyloid-Beta Positivity with 18F-Florbetaben PET on Neuropsychological Aspects in Parkinson’s Disease Dementia
por: Na, Seunghee, et al.
Publicado: (2020)

Technical feasibility of [(18)F]FET and [(18)F]FAZA PET guided radiotherapy in a F98 glioblastoma rat model
por: Verhoeven, Jeroen, et al.
Publicado: (2019)

An Intra-Individual Comparison of MRI, [(18)F]-FET and [(18)F]-FLT PET in Patients with High-Grade Gliomas
por: Nowosielski, Martha, et al.
Publicado: (2014)

(18)F-FET-PET in Primary Hyperparathyroidism: A Pilot Study
por: Krakauer, Martin, et al.
Publicado: (2016)

Glioblastoma PET/MRI: kinetic investigation of [(18)F]rhPSMA-7.3, [(18)F]FET and [(18)F]fluciclovine in an orthotopic mouse model of cancer
por: Lindemann, Marcel, et al.
Publicado: (2022)

On-demand radiosynthesis of N-succinimidyl-4-[(18)F]fluorobenzoate ([(18)F]SFB) on an electrowetting-on-dielectric microfluidic chip for (18)F-labeling of protein
por: Kim, Hee-Kwon, et al.
Publicado: (2019)

In vivo Imaging With (18)F-FDG- and (18)F-Florbetaben-PET/MRI Detects Pathological Changes in the Brain of the Commonly Used 5XFAD Mouse Model of Alzheimer's Disease
por: Franke, Timon N., et al.
Publicado: (2020)

Generation of Conventional (18)F-FDG PET Images from (18)F-Florbetaben PET Images Using Generative Adversarial Network: A Preliminary Study Using ADNI Dataset
por: Choi, Hyung Jin, et al.
Publicado: (2023)

Cross-Sectional Comparison of Small Animal [(18)F]-Florbetaben Amyloid-PET between Transgenic AD Mouse Models
por: Brendel, Matthias, et al.
Publicado: (2015)

Correlation of [(18)F]florbetaben textural features and age of onset of Alzheimer’s disease: a principal components analysis approach
por: Li, Jing, et al.
Publicado: (2021)

Performance evaluation in [(18)F]Florbetaben brain PET images classification using 3D Convolutional Neural Network
por: Lee, Seung-Yeon, et al.
Publicado: (2021)

(18)F-FET and (18)F-choline PET-CT in patients with MRI-suspected low-grade gliomas: a pilot study
por: Mišir Krpan, Ana, et al.
Publicado: (2021)

Non-invasive Early Response Monitoring of Nanoparticle-assisted Photothermal Cancer Therapy Using (18)F-FDG, (18)F-FLT, and (18)F-FET PET/CT Imaging
por: Jørgensen, Jesper Tranekjær, et al.
Publicado: (2018)

Can Radiomics Provide Additional Information in [(18)F]FET-Negative Gliomas?
por: von Rohr, Katharina, et al.
Publicado: (2022)

Synthesis and Evaluation of [(18)F]FEtLos and [(18)F]AMBF(3)Los as Novel (18)F-Labelled Losartan Derivatives for Molecular Imaging of Angiotensin II Type 1 Receptors
por: Sahylí Ortega Pijeira, Martha, et al.
Publicado: (2020)

Uptake of (18)F-FET and (18)F-FCH in Human Glioblastoma T98G Cell Line after Irradiation with Photons or Carbon Ions
por: Pasi, Francesca, et al.
Publicado: (2017)

Ethnic comparison of pharmacokinetics of (18)F-florbetaben, a PET tracer for beta-amyloid imaging, in healthy Caucasian and Japanese subjects
por: Senda, Michio, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_jg35s3gf54n4rr3etmcu5t83ju