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Isolation and identification of marine microbial products
BACKGROUND: The ocean is one of the world’s most important sources of bioactive chemicals in the marine environment. Microbiologists, ecologists, agronomists, taxonomists, and evolutionary biologists have been increasingly interested in marine microbial natural products (MMNPs) in recent decades. MA...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526645/ https://www.ncbi.nlm.nih.gov/pubmed/34665351 http://dx.doi.org/10.1186/s43141-021-00259-3 |
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author | Mohamed, Sahar Saleh Abdelhamid, Sayeda Abdelrazek Ali, Radwa Hassaan |
author_facet | Mohamed, Sahar Saleh Abdelhamid, Sayeda Abdelrazek Ali, Radwa Hassaan |
author_sort | Mohamed, Sahar Saleh |
collection | PubMed |
description | BACKGROUND: The ocean is one of the world’s most important sources of bioactive chemicals in the marine environment. Microbiologists, ecologists, agronomists, taxonomists, and evolutionary biologists have been increasingly interested in marine microbial natural products (MMNPs) in recent decades. MAIN BODY: Diverse marine bacteria appear to get the ability to manufacture an astounding diversity of MMNPs with a wide range of biological actions, including anti-tumor, antimicrobial, and anti-cardiovascular agents according to numerous studies. SHORT CONCLUSIONS: Innovative isolation and culture methodologies, tactics for identifying novel MMNPs via routine screens, metagenomics, genomics, combinatorial biosynthesis, and synthetic biology are all discussed in this review. There is also a discussion of potential issues and future directions for studying MMNPs. |
format | Online Article Text |
id | pubmed-8526645 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-85266452021-11-04 Isolation and identification of marine microbial products Mohamed, Sahar Saleh Abdelhamid, Sayeda Abdelrazek Ali, Radwa Hassaan J Genet Eng Biotechnol Review BACKGROUND: The ocean is one of the world’s most important sources of bioactive chemicals in the marine environment. Microbiologists, ecologists, agronomists, taxonomists, and evolutionary biologists have been increasingly interested in marine microbial natural products (MMNPs) in recent decades. MAIN BODY: Diverse marine bacteria appear to get the ability to manufacture an astounding diversity of MMNPs with a wide range of biological actions, including anti-tumor, antimicrobial, and anti-cardiovascular agents according to numerous studies. SHORT CONCLUSIONS: Innovative isolation and culture methodologies, tactics for identifying novel MMNPs via routine screens, metagenomics, genomics, combinatorial biosynthesis, and synthetic biology are all discussed in this review. There is also a discussion of potential issues and future directions for studying MMNPs. Springer Berlin Heidelberg 2021-10-19 /pmc/articles/PMC8526645/ /pubmed/34665351 http://dx.doi.org/10.1186/s43141-021-00259-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Review Mohamed, Sahar Saleh Abdelhamid, Sayeda Abdelrazek Ali, Radwa Hassaan Isolation and identification of marine microbial products |
title | Isolation and identification of marine microbial products |
title_full | Isolation and identification of marine microbial products |
title_fullStr | Isolation and identification of marine microbial products |
title_full_unstemmed | Isolation and identification of marine microbial products |
title_short | Isolation and identification of marine microbial products |
title_sort | isolation and identification of marine microbial products |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526645/ https://www.ncbi.nlm.nih.gov/pubmed/34665351 http://dx.doi.org/10.1186/s43141-021-00259-3 |
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