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Combined Chaetocin/Trichostatin A Treatment Improves the Epigenetic Modification and Developmental Competence of Porcine Somatic Cell Nuclear Transfer Embryos

Developmental defects in somatic cell nuclear transfer (SCNT) embryos are principally attributable to incomplete epigenetic reprogramming. Small-molecule inhibitors such as histone methyltransferase inhibitors (HMTi) and histone deacetylase inhibitors (HDACi) have been used to improve reprogramming...

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Detalles Bibliográficos
Autores principales:	Jeong, Pil-Soo, Yang, Hae-Jun, Park, Soo-Hyun, Gwon, Min Ah, Joo, Ye Eun, Kim, Min Ju, Kang, Hyo-Gu, Lee, Sanghoon, Park, Young-Ho, Song, Bong-Seok, Kim, Sun-Uk, Koo, Deog-Bon, Sim, Bo-Woong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526721/ https://www.ncbi.nlm.nih.gov/pubmed/34692674 http://dx.doi.org/10.3389/fcell.2021.709574

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