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Drug repurposing improves disease targeting 11-fold and can be augmented by network module targeting, applied to COVID-19
This analysis presents a systematic evaluation of the extent of therapeutic opportunities that can be obtained from drug repurposing by connecting drug targets with disease genes. When using FDA-approved indications as a reference level we found that drug repurposing can offer an average of an 11-fo...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526804/ https://www.ncbi.nlm.nih.gov/pubmed/34667255 http://dx.doi.org/10.1038/s41598-021-99721-y |