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The PDAC Extracellular Matrix: A Review of the ECM Protein Composition, Tumor Cell Interaction, and Therapeutic Strategies

Pancreatic ductal adenocarcinoma (PDAC) is notorious for a dense fibrotic stroma that is interlaced with a collagen-based extracellular matrix (ECM) that plays an important role in tumor biology. Traditionally thought to only provide a physical barrier from host responses and systemic chemotherapy,...

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Detalles Bibliográficos
Autores principales:	Perez, Vincent M., Kearney, Joseph F., Yeh, Jen Jen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526858/ https://www.ncbi.nlm.nih.gov/pubmed/34692532 http://dx.doi.org/10.3389/fonc.2021.751311

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