A novel approach to identify the mechanism of miR-145-5p toxicity to podocytes based on the essential genes targeting analysis

MicroRNAs (miRNAs) are emerging as effective therapeutic agents. When testing whether miR-145-5p could alleviate kidney injury, we unexpectedly found that extracellular vesicles loaded with miR-145-5p induced proteinuria and podocyte foot process effacement in normal control mice. To explore the mec...

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Detalles Bibliográficos
Autores principales: Zhang, Sipan, Wu, Junnan, Zhu, Xiaodong, Song, Hui, Ren, Lu, Tang, Qiaoli, Xu, Xiaodong, Liu, Chunbei, Zhang, Jiong, Hu, Weixin, Liu, Zhihong, Shi, Shaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526908/
https://www.ncbi.nlm.nih.gov/pubmed/34729245
http://dx.doi.org/10.1016/j.omtn.2021.09.005

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