Cargando…
Characterization of the Cancer-Associated Meprin Βeta Variants G45R and G89R
Meprin β is a metalloprotease associated with neurodegeneration, inflammation, extracellular matrix homeostasis, transendothelial cell migration, and cancer. In this study, we investigated two melanoma-associated variants of meprin β, both exhibiting a single amino acid exchange, namely, meprin β G4...
Autores principales: | Gellrich, Antonin, Scharfenberg, Franka, Peters, Florian, Sammel, Martin, Helm, Ole, Armbrust, Fred, Schmidt, Frederike, Lokau, Juliane, Garbers, Christoph, Sebens, Susanne, Arnold, Philipp, Becker-Pauly, Christoph |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526939/ https://www.ncbi.nlm.nih.gov/pubmed/34692768 http://dx.doi.org/10.3389/fmolb.2021.702341 |
Ejemplares similares
-
Differences in Shedding of the Interleukin-11 Receptor by the Proteases ADAM9, ADAM10, ADAM17, Meprin α, Meprin β and MT1-MMP
por: Sammel, Martin, et al.
Publicado: (2019) -
Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling
por: Arnold, Philipp, et al.
Publicado: (2017) -
Proteolytic processing of galectin-3 by meprin metalloproteases is crucial for host-microbiome homeostasis
por: Bülck, Cynthia, et al.
Publicado: (2023) -
The metalloproteases meprin α and meprin β: unique enzymes in inflammation, neurodegeneration, cancer and fibrosis
por: Broder, Claudia, et al.
Publicado: (2013) -
Cancer-associated mutations in the canonical cleavage site do not influence CD99 shedding by the metalloprotease meprin β but alter cell migration in vitro
por: Bedau, Tillmann, et al.
Publicado: (2017)