The predicted stem-loop structure in the 3′-end of the human norovirus antigenomic sequence is required for its genomic RNA synthesis by its RdRp

The norovirus genome consists of a single positive-stranded RNA. The mechanism by which this single-stranded RNA genome is replicated is not well understood. To reveal the mechanism underlying the initiation of the norovirus genomic RNA synthesis by its RNA-dependent RNA polymerase (RdRp), we used a...

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Detalles Bibliográficos
Autores principales: Shimoike, Takashi, Hayashi, Tsuyoshi, Oka, Tomoichiro, Muramatsu, Masamichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526979/
https://www.ncbi.nlm.nih.gov/pubmed/34562449
http://dx.doi.org/10.1016/j.jbc.2021.101225

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