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Characterization of IncHI1B Plasmids Encoding Efflux Pump TmexCD2-ToprJ2 in Carbapenem-Resistant Klebsiella variicola, Klebsiella quasipneumoniae, and Klebsiella michiganensis Strains

Tigecycline serves as one of the last-resort antibiotics to treat severe infections caused by carbapenem-resistant Enterobacterales. Recently, a novel plasmid-mediated resistance-nodulation-division (RND)-type efflux pump gene cluster, TmexCD1-ToprJ1, and its variants, TmexCD2-ToprJ2 and TmexCD3-Top...

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Detalles Bibliográficos
Autores principales: Wang, Yujiao, Zhu, Bo, Liu, Min, Dong, Xiutao, Ma, Jianping, Li, Xiaofeng, Cheng, Fang, Guo, Jianzhuang, Lu, Sumei, Wan, Furong, Hao, Yingying, Ma, Wanshan, Hao, Mingju, Chen, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527040/
https://www.ncbi.nlm.nih.gov/pubmed/34691010
http://dx.doi.org/10.3389/fmicb.2021.759208