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MET overexpression contributes to STAT4-PD-L1 signaling activation associated with tumor-associated, macrophages-mediated immunosuppression in primary glioblastomas

BACKGROUND: Dysregulated receptor tyrosine kinases, such as the mesenchymal-epidermal transition factor (MET), have pivotal role in gliomas. MET and its interaction with the tumor microenvironment have been previously implicated in secondary gliomas. However, the contribution of MET gene to tumor ce...

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Detalles Bibliográficos
Autores principales:	Wang, Qiang-Wei, Sun, Li-Hua, Zhang, Ying, Wang, Zheng, Zhao, Zheng, Wang, Zhi-Liang, Wang, Kuan-Yu, Li, Guan-Zhang, Xu, Jian-Bao, Ren, Chang-Yuan, Ma, Wen-Ping, Wang, Hong-Jun, Li, Shou-Wei, Zhu, Yong-Jian, Jiang, Tao, Bao, Zhao-Shi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Immunotherapy Biomarkers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527154/ https://www.ncbi.nlm.nih.gov/pubmed/34667077 http://dx.doi.org/10.1136/jitc-2021-002451

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