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LN Monocytes Limit DC-Poly I:C Induced Cytotoxic T Cell Response via IL-10 and Induction of Suppressor CD4 T Cells

Every immune response has accelerators and brakes. Depending on the pathogen or injury, monocytes can play either role, promoting or resolving immunity. Poly I:C, a potent TLR3 ligand, licenses cross-presenting dendritic cells (DC1) to accelerate a robust cytotoxic T cells response against a foreign...

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Detalles Bibliográficos
Autores principales:	Tewari, Anita, Prabagar, Miglena G., Gibbings, Sophie L., Rawat, Kavita, Jakubzick, Claudia V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527167/ https://www.ncbi.nlm.nih.gov/pubmed/34691085 http://dx.doi.org/10.3389/fimmu.2021.763379

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