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Stamp2 Protects From Maladaptive Structural Remodeling and Systolic Dysfunction in Post-Ischemic Hearts by Attenuating Neutrophil Activation

The six-transmembrane protein of prostate 2 (Stamp2) acts as an anti-inflammatory protein in macrophages by protecting from overt inflammatory signaling and Stamp2 deficiency accelerates atherosclerosis in mice. Herein, we describe an unexpected role of Stamp2 in polymorphonuclear neutrophils (PMN)...

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Detalles Bibliográficos
Autores principales: Mollenhauer, Martin, Bokredenghel, Senai, Geißen, Simon, Klinke, Anna, Morstadt, Tobias, Torun, Merve, Strauch, Sabrina, Schumacher, Wibke, Maass, Martina, Konradi, Jürgen, Peters, Vera B. M., Berghausen, Eva, Vantler, Marius, Rosenkranz, Stephan, Mehrkens, Dennis, Braumann, Simon, Nettersheim, Felix, Hof, Alexander, Simsekyilmaz, Sakine, Winkels, Holger, Rudolph, Volker, Baldus, Stephan, Adam, Matti, Freyhaus, Henrik ten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527169/
https://www.ncbi.nlm.nih.gov/pubmed/34691017
http://dx.doi.org/10.3389/fimmu.2021.701721