Aligned nanofiber nerve conduits inhibit alpha smooth muscle actin expression and collagen proliferation by suppressing TGF-β1/SMAD signaling in traumatic neuromas

Transforming growth factor-beta 1 (TGF-β1) is a powerful activator of connective tissue synthesis that is strongly associated with the pathophysiology of traumatic neuroma. Previous studies have demonstrated that aligned nanofiber conduits made from silk fibroin and poly (L-lactic acid-co-ε-caprolac...

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Detalles Bibliográficos
Autores principales: Yao, Chenglun, Zhou, Xijie, Weng, Weidong, Poonit, Keshav, Sun, Chao, Yan, Hede
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527191/
https://www.ncbi.nlm.nih.gov/pubmed/34676007
http://dx.doi.org/10.3892/etm.2021.10850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527191/
https://www.ncbi.nlm.nih.gov/pubmed/34676007
http://dx.doi.org/10.3892/etm.2021.10850

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