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Aligned nanofiber nerve conduits inhibit alpha smooth muscle actin expression and collagen proliferation by suppressing TGF-β1/SMAD signaling in traumatic neuromas
Transforming growth factor-beta 1 (TGF-β1) is a powerful activator of connective tissue synthesis that is strongly associated with the pathophysiology of traumatic neuroma. Previous studies have demonstrated that aligned nanofiber conduits made from silk fibroin and poly (L-lactic acid-co-ε-caprolac...
Autores principales: | Yao, Chenglun, Zhou, Xijie, Weng, Weidong, Poonit, Keshav, Sun, Chao, Yan, Hede |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527191/ https://www.ncbi.nlm.nih.gov/pubmed/34676007 http://dx.doi.org/10.3892/etm.2021.10850 |
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