Safety and Immune Effects of Blocking CD40 Ligand in Multiple Sclerosis

BACKGROUND AND OBJECTIVES: Costimulation by CD40 and its ligand CD40L (CD154) is important for the functional differentiation of T cells. Preclinical studies have recognized the importance of this costimulatory interaction in the pathogenesis of experimental models of multiple sclerosis (MS). To det...

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Detalles Bibliográficos
Autores principales: Fadul, Camilo E., Mao-Draayer, Yang, Ryan, Kathleen A., Noelle, Randolph J., Wishart, Heather A., Channon, Jacqueline Y., Kasper, Isaac R., Oliver, Brant, Mielcarz, Daniel W., Kasper, Lloyd H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527364/
https://www.ncbi.nlm.nih.gov/pubmed/34654708
http://dx.doi.org/10.1212/NXI.0000000000001096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527364/
https://www.ncbi.nlm.nih.gov/pubmed/34654708
http://dx.doi.org/10.1212/NXI.0000000000001096

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