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Identification of sample mix-ups and mixtures in microbiome data in Diversity Outbred mice

In a Diversity Outbred mouse project with genotype data on 500 mice, including 297 with microbiome data, we identified three sets of sample mix-ups (two pairs and one trio) as well as at least 15 microbiome samples that appear to be mixtures of pairs of mice. The microbiome data consisted of shotgun...

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Detalles Bibliográficos
Autores principales: Lobo, Alexandra K, Traeger, Lindsay L, Keller, Mark P, Attie, Alan D, Rey, Federico E, Broman, Karl W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527510/
https://www.ncbi.nlm.nih.gov/pubmed/34499168
http://dx.doi.org/10.1093/g3journal/jkab308