Genetic screen for suppressors of increased silencing in rpd3 mutants in Saccharomyces cerevisiae identifies a potential role for H3K4 methylation

Several studies have identified the paradoxical phenotype of increased heterochromatic gene silencing at specific loci that results from deletion or mutation of the histone deacetylase (HDAC) gene RPD3. To further understand this phenomenon, we conducted a genetic screen for suppressors of this exte...

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Detalles Bibliográficos
Autores principales: Kleinschmidt, Richard A, Lyon, Laurie M, Smith, Samantha L, Rittenberry, Jonah, Lawless, K Maeve, Acosta, Anabelle A, Donze, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Mutant Screen Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527511/
https://www.ncbi.nlm.nih.gov/pubmed/34534290
http://dx.doi.org/10.1093/g3journal/jkab309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527511/
https://www.ncbi.nlm.nih.gov/pubmed/34534290
http://dx.doi.org/10.1093/g3journal/jkab309

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