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Genetic screen for suppressors of increased silencing in rpd3 mutants in Saccharomyces cerevisiae identifies a potential role for H3K4 methylation
Several studies have identified the paradoxical phenotype of increased heterochromatic gene silencing at specific loci that results from deletion or mutation of the histone deacetylase (HDAC) gene RPD3. To further understand this phenomenon, we conducted a genetic screen for suppressors of this exte...
Autores principales: | Kleinschmidt, Richard A, Lyon, Laurie M, Smith, Samantha L, Rittenberry, Jonah, Lawless, K Maeve, Acosta, Anabelle A, Donze, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527511/ https://www.ncbi.nlm.nih.gov/pubmed/34534290 http://dx.doi.org/10.1093/g3journal/jkab309 |
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