A systems approach using Diversity Outbred mice distinguishes the cardiovascular effects and genetics of circulating GDF11 from those of its homolog, myostatin

Growth differentiation factor 11 (GDF11) is a member of the TGF-β protein family that has been implicated in the development of cardiac hypertrophy. While some studies have suggested that systemic GDF11 protects against cardiomyocyte enlargement and left ventricular wall thickening, there remains un...

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Detalles Bibliográficos
Autores principales: Starcher, Abigail E, Peissig, Kristen, Stanton, James B, Churchill, Gary A, Cai, Dunpeng, Maxwell, Joshua T, Grider, Arthur, Love, Kim, Chen, Shi-You, Coleman, Amanda E, Strauss, Emma, Pazdro, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527520/
https://www.ncbi.nlm.nih.gov/pubmed/34510201
http://dx.doi.org/10.1093/g3journal/jkab293

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