Cargando…
Prediction of synergistic drug combinations using PCA-initialized deep learning
BACKGROUND: Cancer is one of the main causes of death worldwide. Combination drug therapy has been a mainstay of cancer treatment for decades and has been shown to reduce host toxicity and prevent the development of acquired drug resistance. However, the immense number of possible drug combinations...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527604/ https://www.ncbi.nlm.nih.gov/pubmed/34670583 http://dx.doi.org/10.1186/s13040-021-00278-3 |