HMGB1 mediates cognitive impairment caused by the NLRP3 inflammasome in the late stage of traumatic brain injury

BACKGROUND: Cognitive impairment in the late stage of traumatic brain injury (TBI) is associated with the NOD-, LRR and pyrin domain-containing protein 3 (NLRP3) inflammasome, which plays an important role in neuroinflammation. Although classical inflammatory pathways have been well-documented in th...

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Detalles Bibliográficos
Autores principales: Tan, Si-Wei, Zhao, Yan, Li, Ping, Ning, Ya-Lei, Huang, Zhi-Zhong, Yang, Nan, Liu, Dong, Zhou, Yuan-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527642/
https://www.ncbi.nlm.nih.gov/pubmed/34666797
http://dx.doi.org/10.1186/s12974-021-02274-0

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