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The Saudi Critical Care Society practice guidelines on the management of COVID-19 in the ICU: Therapy section
BACKGROUND: The rapid increase in coronavirus disease 2019 (COVID-19) cases during the subsequent waves in Saudi Arabia and other countries prompted the Saudi Critical Care Society (SCCS) to put together a panel of experts to issue evidence-based recommendations for the management of COVID-19 in the...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527699/ https://www.ncbi.nlm.nih.gov/pubmed/34764042 http://dx.doi.org/10.1016/j.jiph.2021.10.005 |
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author | Alhazzani, Waleed Alshahrani, Mohammed Alshamsi, Fayez Aljuhani, Ohoud Eljaaly, Khalid Hashim, Samaher Alqahtani, Rakan Alsaleh, Doaa Al Duhailib, Zainab Algethamy, Haifa Al-Musawi, Tariq Alshammari, Thamir Alqarni, Abdullah Khoujah, Danya Tashkandi, Wail Dahhan, Talal Almutairi, Najla Alserehi, Haleema A. Al-Yahya, Maytha Al-Judaibi, Bandar Arabi, Yaseen M. Abualenain, Jameel Alotaibi, Jawaher M. Al bshabshe, Ali Alharbi, Reham Al-Hameed, Fahad Elhazmi, Alyaa Almaghrabi, Reem S. Almaghlouth, Fatma Abedalthagafi, Malak Al Khathlan, Noor Al-Suwaidan, Faisal A. Bunyan, Reem F. Baw, Bandar Alghamdi, Ghassan Al Hazmi, Manal Mandourah, Yasser Assiri, Abdullah Enani, Mushira Alawi, Maha Aljindan, Reem Aljabbary, Ahmed Alrbiaan, Abdullah Algurashi, Fahd Alsaawi, Abdulmohsen Alenazi, Thamer H. Alsultan, Mohammed A. Alqahtani, Saleh A. Memish, Ziad Al-Tawfiq, Jaffar A. Al-jedai, Ahmed |
author_facet | Alhazzani, Waleed Alshahrani, Mohammed Alshamsi, Fayez Aljuhani, Ohoud Eljaaly, Khalid Hashim, Samaher Alqahtani, Rakan Alsaleh, Doaa Al Duhailib, Zainab Algethamy, Haifa Al-Musawi, Tariq Alshammari, Thamir Alqarni, Abdullah Khoujah, Danya Tashkandi, Wail Dahhan, Talal Almutairi, Najla Alserehi, Haleema A. Al-Yahya, Maytha Al-Judaibi, Bandar Arabi, Yaseen M. Abualenain, Jameel Alotaibi, Jawaher M. Al bshabshe, Ali Alharbi, Reham Al-Hameed, Fahad Elhazmi, Alyaa Almaghrabi, Reem S. Almaghlouth, Fatma Abedalthagafi, Malak Al Khathlan, Noor Al-Suwaidan, Faisal A. Bunyan, Reem F. Baw, Bandar Alghamdi, Ghassan Al Hazmi, Manal Mandourah, Yasser Assiri, Abdullah Enani, Mushira Alawi, Maha Aljindan, Reem Aljabbary, Ahmed Alrbiaan, Abdullah Algurashi, Fahd Alsaawi, Abdulmohsen Alenazi, Thamer H. Alsultan, Mohammed A. Alqahtani, Saleh A. Memish, Ziad Al-Tawfiq, Jaffar A. Al-jedai, Ahmed |
author_sort | Alhazzani, Waleed |
collection | PubMed |
description | BACKGROUND: The rapid increase in coronavirus disease 2019 (COVID-19) cases during the subsequent waves in Saudi Arabia and other countries prompted the Saudi Critical Care Society (SCCS) to put together a panel of experts to issue evidence-based recommendations for the management of COVID-19 in the intensive care unit (ICU). METHODS: The SCCS COVID-19 panel included 51 experts with expertise in critical care, respirology, infectious disease, epidemiology, emergency medicine, clinical pharmacy, nursing, respiratory therapy, methodology, and health policy. All members completed an electronic conflict of interest disclosure form. The panel addressed 9 questions that are related to the therapy of COVID-19 in the ICU. We identified relevant systematic reviews and clinical trials, then used the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach as well as the evidence-to-decision framework (EtD) to assess the quality of evidence and generate recommendations. RESULTS: The SCCS COVID-19 panel issued 12 recommendations on pharmacotherapeutic interventions (immunomodulators, antiviral agents, and anticoagulants) for severe and critical COVID-19, of which 3 were strong recommendations and 9 were weak recommendations. CONCLUSION: The SCCS COVID-19 panel used the GRADE approach to formulate recommendations on therapy for COVID-19 in the ICU. The EtD framework allows adaptation of these recommendations in different contexts. The SCCS guideline committee will update recommendations as new evidence becomes available. |
format | Online Article Text |
id | pubmed-8527699 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences. |
record_format | MEDLINE/PubMed |
spelling | pubmed-85276992021-10-21 The Saudi Critical Care Society practice guidelines on the management of COVID-19 in the ICU: Therapy section Alhazzani, Waleed Alshahrani, Mohammed Alshamsi, Fayez Aljuhani, Ohoud Eljaaly, Khalid Hashim, Samaher Alqahtani, Rakan Alsaleh, Doaa Al Duhailib, Zainab Algethamy, Haifa Al-Musawi, Tariq Alshammari, Thamir Alqarni, Abdullah Khoujah, Danya Tashkandi, Wail Dahhan, Talal Almutairi, Najla Alserehi, Haleema A. Al-Yahya, Maytha Al-Judaibi, Bandar Arabi, Yaseen M. Abualenain, Jameel Alotaibi, Jawaher M. Al bshabshe, Ali Alharbi, Reham Al-Hameed, Fahad Elhazmi, Alyaa Almaghrabi, Reem S. Almaghlouth, Fatma Abedalthagafi, Malak Al Khathlan, Noor Al-Suwaidan, Faisal A. Bunyan, Reem F. Baw, Bandar Alghamdi, Ghassan Al Hazmi, Manal Mandourah, Yasser Assiri, Abdullah Enani, Mushira Alawi, Maha Aljindan, Reem Aljabbary, Ahmed Alrbiaan, Abdullah Algurashi, Fahd Alsaawi, Abdulmohsen Alenazi, Thamer H. Alsultan, Mohammed A. Alqahtani, Saleh A. Memish, Ziad Al-Tawfiq, Jaffar A. Al-jedai, Ahmed J Infect Public Health Original Article BACKGROUND: The rapid increase in coronavirus disease 2019 (COVID-19) cases during the subsequent waves in Saudi Arabia and other countries prompted the Saudi Critical Care Society (SCCS) to put together a panel of experts to issue evidence-based recommendations for the management of COVID-19 in the intensive care unit (ICU). METHODS: The SCCS COVID-19 panel included 51 experts with expertise in critical care, respirology, infectious disease, epidemiology, emergency medicine, clinical pharmacy, nursing, respiratory therapy, methodology, and health policy. All members completed an electronic conflict of interest disclosure form. The panel addressed 9 questions that are related to the therapy of COVID-19 in the ICU. We identified relevant systematic reviews and clinical trials, then used the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach as well as the evidence-to-decision framework (EtD) to assess the quality of evidence and generate recommendations. RESULTS: The SCCS COVID-19 panel issued 12 recommendations on pharmacotherapeutic interventions (immunomodulators, antiviral agents, and anticoagulants) for severe and critical COVID-19, of which 3 were strong recommendations and 9 were weak recommendations. CONCLUSION: The SCCS COVID-19 panel used the GRADE approach to formulate recommendations on therapy for COVID-19 in the ICU. The EtD framework allows adaptation of these recommendations in different contexts. The SCCS guideline committee will update recommendations as new evidence becomes available. Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences. 2022-01 2021-10-20 /pmc/articles/PMC8527699/ /pubmed/34764042 http://dx.doi.org/10.1016/j.jiph.2021.10.005 Text en © 2021 Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Original Article Alhazzani, Waleed Alshahrani, Mohammed Alshamsi, Fayez Aljuhani, Ohoud Eljaaly, Khalid Hashim, Samaher Alqahtani, Rakan Alsaleh, Doaa Al Duhailib, Zainab Algethamy, Haifa Al-Musawi, Tariq Alshammari, Thamir Alqarni, Abdullah Khoujah, Danya Tashkandi, Wail Dahhan, Talal Almutairi, Najla Alserehi, Haleema A. Al-Yahya, Maytha Al-Judaibi, Bandar Arabi, Yaseen M. Abualenain, Jameel Alotaibi, Jawaher M. Al bshabshe, Ali Alharbi, Reham Al-Hameed, Fahad Elhazmi, Alyaa Almaghrabi, Reem S. Almaghlouth, Fatma Abedalthagafi, Malak Al Khathlan, Noor Al-Suwaidan, Faisal A. Bunyan, Reem F. Baw, Bandar Alghamdi, Ghassan Al Hazmi, Manal Mandourah, Yasser Assiri, Abdullah Enani, Mushira Alawi, Maha Aljindan, Reem Aljabbary, Ahmed Alrbiaan, Abdullah Algurashi, Fahd Alsaawi, Abdulmohsen Alenazi, Thamer H. Alsultan, Mohammed A. Alqahtani, Saleh A. Memish, Ziad Al-Tawfiq, Jaffar A. Al-jedai, Ahmed The Saudi Critical Care Society practice guidelines on the management of COVID-19 in the ICU: Therapy section |
title | The Saudi Critical Care Society practice guidelines on the management of COVID-19 in the ICU: Therapy section |
title_full | The Saudi Critical Care Society practice guidelines on the management of COVID-19 in the ICU: Therapy section |
title_fullStr | The Saudi Critical Care Society practice guidelines on the management of COVID-19 in the ICU: Therapy section |
title_full_unstemmed | The Saudi Critical Care Society practice guidelines on the management of COVID-19 in the ICU: Therapy section |
title_short | The Saudi Critical Care Society practice guidelines on the management of COVID-19 in the ICU: Therapy section |
title_sort | saudi critical care society practice guidelines on the management of covid-19 in the icu: therapy section |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527699/ https://www.ncbi.nlm.nih.gov/pubmed/34764042 http://dx.doi.org/10.1016/j.jiph.2021.10.005 |
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