Initial clinical manifestation of multiple sclerosis after immunization with the Pfizer-BioNTech COVID-19 vaccine

Vaccine administration may be involved in the development of some central nervous system demyelinating diseases. The COVID-19 vaccine is being administered to the entire population, but to date, little association between vaccination and the risk of developing multiple sclerosis (MS) has been sugges...

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Detalles Bibliográficos
Autores principales: Fujimori, Juichi, Miyazawa, Kouichi, Nakashima, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527738/
https://www.ncbi.nlm.nih.gov/pubmed/34700047
http://dx.doi.org/10.1016/j.jneuroim.2021.577755
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author Fujimori, Juichi
Miyazawa, Kouichi
Nakashima, Ichiro
author_facet Fujimori, Juichi
Miyazawa, Kouichi
Nakashima, Ichiro
author_sort Fujimori, Juichi
collection PubMed
description Vaccine administration may be involved in the development of some central nervous system demyelinating diseases. The COVID-19 vaccine is being administered to the entire population, but to date, little association between vaccination and the risk of developing multiple sclerosis (MS) has been suggested, and only a few case reports have been published. Here, we present a 40-year-old woman who developed cervical myelitis after receiving the COVID-19 vaccine. Myelitis was considered the initial clinical manifestation of MS. Our case suggests a possible link between the vaccination and the clinical MS attack.
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spelling pubmed-85277382021-10-21 Initial clinical manifestation of multiple sclerosis after immunization with the Pfizer-BioNTech COVID-19 vaccine Fujimori, Juichi Miyazawa, Kouichi Nakashima, Ichiro J Neuroimmunol Short Communication Vaccine administration may be involved in the development of some central nervous system demyelinating diseases. The COVID-19 vaccine is being administered to the entire population, but to date, little association between vaccination and the risk of developing multiple sclerosis (MS) has been suggested, and only a few case reports have been published. Here, we present a 40-year-old woman who developed cervical myelitis after receiving the COVID-19 vaccine. Myelitis was considered the initial clinical manifestation of MS. Our case suggests a possible link between the vaccination and the clinical MS attack. Elsevier B.V. 2021-12-15 2021-10-20 /pmc/articles/PMC8527738/ /pubmed/34700047 http://dx.doi.org/10.1016/j.jneuroim.2021.577755 Text en © 2021 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Short Communication
Fujimori, Juichi
Miyazawa, Kouichi
Nakashima, Ichiro
Initial clinical manifestation of multiple sclerosis after immunization with the Pfizer-BioNTech COVID-19 vaccine
title Initial clinical manifestation of multiple sclerosis after immunization with the Pfizer-BioNTech COVID-19 vaccine
title_full Initial clinical manifestation of multiple sclerosis after immunization with the Pfizer-BioNTech COVID-19 vaccine
title_fullStr Initial clinical manifestation of multiple sclerosis after immunization with the Pfizer-BioNTech COVID-19 vaccine
title_full_unstemmed Initial clinical manifestation of multiple sclerosis after immunization with the Pfizer-BioNTech COVID-19 vaccine
title_short Initial clinical manifestation of multiple sclerosis after immunization with the Pfizer-BioNTech COVID-19 vaccine
title_sort initial clinical manifestation of multiple sclerosis after immunization with the pfizer-biontech covid-19 vaccine
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527738/
https://www.ncbi.nlm.nih.gov/pubmed/34700047
http://dx.doi.org/10.1016/j.jneuroim.2021.577755
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