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Blockade of the NLRP3/caspase-1 axis attenuates ketamine-induced hippocampus pyroptosis and cognitive impairment in neonatal rats

BACKGROUND: Multiple studies have revealed that repeated or long-term exposure to ketamine causes neurodegeneration and cognitive dysfunction. Pyroptosis is an inflammatory form of programmed cell death that has been linked to various neurological diseases. However, the role of NLRP3/caspase-1 axis-...

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Detalles Bibliográficos
Autores principales:	Zhang, Zhiheng, Bai, Hui, Ma, Xiangying, Shen, Meilun, Li, Rouqian, Qiu, Di, Li, Siyao, Gao, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527745/ https://www.ncbi.nlm.nih.gov/pubmed/34666787 http://dx.doi.org/10.1186/s12974-021-02295-9

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