Inhibition of lysophosphatidic acid receptor 1–3 deteriorates experimental autoimmune encephalomyelitis by inducing oxidative stress

BACKGROUND: Lysophosphatidic acid receptors (LPARs) are G-protein-coupled receptors involved in many physiological functions in the central nervous system. However, the role of the LPARs in multiple sclerosis (MS) has not been clearly defined yet. METHODS: Here, we investigated the roles of LPARs in...

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Detalles Bibliográficos
Autores principales: Choi, Jong Hee, Oh, Jinhee, Lee, Min Jung, Bae, Hyunsu, Ko, Seong-Gyu, Nah, Seung-Yeol, Cho, Ik-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527776/
https://www.ncbi.nlm.nih.gov/pubmed/34666785
http://dx.doi.org/10.1186/s12974-021-02278-w

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