Efficacy and safety of dual intravenous artesunate plus quinine compared to intravenous artesunate for cerebral malaria in a triple blinded parallel multisite randomized controlled trial in Nigerian children: DUAL PAQ TRIAL Protocol

BACKGROUND: Evidence exists as to the criticality of the first 24 h in the management of cerebral malaria. The morbidity and the mortality rate (35%) with the current intravenous monotherapy for the initial treatment of cerebral malaria are unacceptably high. Combination therapy and a shorter course...

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Detalles Bibliográficos
Autores principales: Alao, Michael Abel, Orimadegun, Adebola Emmanuel, Ibrahim, Olayinka Rasheed, Oyenuga, Abayomi O., Asinobi, Adanze Onyenonachi, Gbadero, Daniel Adedosu, Okoye, Ifeoma Joy, Nna, Emmanuel Okechukwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527777/
https://www.ncbi.nlm.nih.gov/pubmed/34670598
http://dx.doi.org/10.1186/s13063-021-05634-6

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